Tumour histology and primary site but not MDM2 amplification levels are prognostic for clinical outcomes in well differentiated and dedifferentiated liposarcoma

被引:0
|
作者
Chew, W. H. W. [1 ]
Chan, J. Y. [1 ]
Goh, W. L. [1 ]
Lim, J. H. C. [2 ]
Tan, S. H. [2 ]
Somasundaram, N. [1 ]
Poon, E. Y. L. [1 ]
Lim, A. S. T. [3 ]
Tan, M. H. [4 ]
Soo, K. C. [5 ]
Teo, M. [5 ]
Tay, T. K. Y. [6 ]
Selvarajan, S. [6 ]
Sittampalam, K. [6 ]
Quek, R. [1 ]
机构
[1] Natl Canc Ctr Singapore, Div Med Oncol, Singapore, Singapore
[2] Natl Canc Ctr Singapore, Div Clin Trials & Epidemiol Sci, Singapore, Singapore
[3] Singapore Gen Hosp, Dept Mol Pathol, Singapore, Singapore
[4] Singapore Gen Hosp, Dept Orthopaed Surg, Singapore, Singapore
[5] Natl Canc Ctr Singapore, Div Surg Oncol, Singapore, Singapore
[6] Singapore Gen Hosp, Dept Anat Pathol, Singapore, Singapore
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
487O
引用
收藏
页码:150 / 150
页数:1
相关论文
共 50 条
  • [31] Well-Differentiated Liposarcoma of the Hypopharynx Exhibiting Myxoid Liposarcoma-like Morphology with MDM2 and DDIT3 Co-Amplification
    Murshed, Khaled A.
    Abo Samra, Hayan
    Ammar, Adham
    HEAD & NECK PATHOLOGY, 2022, 16 (01): : 288 - 293
  • [32] Prognostic relevance of Federation Nationale des Centres de Lutte Contre le Cancer grade and MDM2 amplification levels in dedifferentiated liposarcoma: a study of 50 cases
    Jour, George
    Gullet, Ashley
    Liu, Mingdong
    Hoch, Benjamin L.
    MODERN PATHOLOGY, 2015, 28 (01) : 37 - 47
  • [33] High level of CDK4 amplification is a poor prognostic factor in well-differentiated and dedifferentiated liposarcoma
    Lee, Seung Eun
    Kim, Yu Jin
    Kwon, Mi Jeong
    Choi, Dong Ill
    Lee, Jeeyun
    Cho, Junhun
    Seo, Sung Wook
    Kim, Sung Joo
    Shin, Young Kee
    Choi, Yoon-La
    HISTOLOGY AND HISTOPATHOLOGY, 2014, 29 (01) : 127 - 138
  • [34] Negative MDM2/CDK4 immunoreactivity does not fully exclude MDM2/CDK4 amplification in a subset of atypical lipomatous tumor/well differentiated liposarcoma
    Machado, Isidro
    Vargas, A. Cristina
    Maclean, Fiona
    Llombart-Bosch, Antonio
    PATHOLOGY RESEARCH AND PRACTICE, 2022, 232
  • [35] Differential diagnosis of atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: utility of p16 in combination with MDM2 and CDK4 immunohistochemistry
    Kammerer-Jacquet, Solene-Florence
    Thierry, Sixte
    Cabillic, Florian
    Lannes, Morgane
    Burtin, Florence
    Henno, Sebastien
    Dugay, Frederic
    Bouzille, Guillaume
    Rioux-Leclercq, Nathalie
    Belaud-Rotureau, Marc-Antoine
    Stock, Nathalie
    HUMAN PATHOLOGY, 2017, 59 : 34 - 40
  • [36] Milademetan, an oral MDM2 inhibitor, in well-differentiated/dedifferentiated liposarcoma: results from a phase 1 study in patients with solid tumors or lymphomas
    Gounder, M. M.
    Bauer, T. M.
    Schwartz, G. K.
    LoRusso, P.
    Kumar, P.
    Kato, K.
    Tao, B.
    Hong, Y.
    Patel, P.
    Hong, D.
    EUROPEAN JOURNAL OF CANCER, 2020, 138 : S3 - S4
  • [37] IGF2BP3 as a Prognostic Biomarker in Well-Differentiated/Dedifferentiated Liposarcoma
    Klingbeil, Kyle D.
    Tang, Jack Pengfei
    Graham, Danielle S.
    Lofftus, Serena Y.
    Jaiswal, Amit Kumar
    Lin, Tasha L.
    Frias, Chris
    Chen, Lucia Y.
    Nakasaki, Manando
    Dry, Sarah M.
    Crompton, Joseph G.
    Eilber, Fritz C.
    Rao, Dinesh S.
    Kalbasi, Anusha
    Kadera, Brian E.
    CANCERS, 2023, 15 (18)
  • [38] Detection of MDM2 Gene Amplification or Protein Expression Distinguishes Sclerosing Mesenteritis and Retroperitoneal Fibrosis from Inflammatory Well Differentiated Liposarcoma
    Weaver, J.
    Goldblum, J. R.
    Turner, S.
    Tubbs, R. R.
    Wang, W.
    Lazar, A. J.
    Rubin, B. P.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2008, 10 (06): : 608 - 609
  • [39] Detection of MDM2 amplification by shallow whole genome sequencing of cell-free DNA of patients with dedifferentiated liposarcoma
    Przybyl, Joanna
    Spans, Lien
    Ganjoo, Kristen
    Bui, Nam
    Mohler, David
    Norton, Jeffrey
    Poultsides, George
    Debiec-Rychter, Maria
    van de Rijn, Matt
    PLOS ONE, 2022, 17 (01):
  • [40] MDM2 Amplification in Atypical Lipomatous Tumors/Well-Differentiated Liposarcomas and Dedifferentiated Liposarcomas: A Comparative RT-PCR and FISH Study
    Willems, J. G.
    Gjihaderi, M.
    Olsson, A.
    Lestrin, M.
    Elmberger, G.
    LABORATORY INVESTIGATION, 2010, 90 : 393A - 393A