DNA microarrays are a powerful tool for the analysis of RNA and DNA composition on a whole-genome scale. The first applications of this technology in parasitology are in place. This review examines the various approaches to Plasmodium transcript-profiling that are being adopted using DNA microarray analysis and discusses additional strategies for obtaining and collating information relevant to the search for drug and vaccine candidates in malaria.
机构:
Univ Ljubljana, Dept Mol Genet, Inst Pathol, Fac Med, Zaloska 4, Ljubljana 1000, SloveniaUniv Ljubljana, Dept Mol Genet, Inst Pathol, Fac Med, Zaloska 4, Ljubljana 1000, Slovenia