Long-term safety profile of pembrolizumab monotherapy and relationship with clinical outcome: A pooled analysis of patients with advanced melanoma

被引：1
|
作者：
Hamid, O. [1 ]
Joshua, A. M. [2 ]
Hwu, W-J. [3 ]
Ribas, A. [4 ]
Weber, J. [5 ]
Daud, A. S. [6 ]
Hodi, F. S. [7 ]
Wolchok, J. D. [8 ]
Mitchell, T. C. [9 ]
Hersey, P. [10 ]
Dronca, R. [11 ]
Joseph, R. W. [12 ]
Boutros, C. [13 ]
Min, L. [14 ,15 ]
Long, G. V. [16 ]
Schachter, J. [17 ]
Lin, J. [18 ]
Ibrahim, N. [18 ]
Carlino, M. [10 ]
Robert, C. [13 ]
机构：
[1] Angeles Clin & Res Inst, Dept Oncol, Los Angeles, CA USA
[2] St Vincents Hosp, Kinghorn Canc Ctr, Dept Med Oncol, Sydney, NSW, Australia
[3] Univ Texas MD Anderson Canc Ctr, Dept Melanoma Med Oncol, Houston, TX 77030 USA
[4] Univ Calif Los Angeles, Dept Med, Div Hematol Oncol, Los Angeles, CA 90024 USA
[5] NYU Langone Hlth, Perlmutter Canc Ctr, Med Oncol, New York, NY USA
[6] UCSF, Dept Hematol Oncol, San Francisco, CA USA
[7] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA
[8] Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USA
[9] Penn Med, Abramson Canc Ctr, Div Hematol & Oncol, Philadelphia, PA USA
[10] Univ Sydney, Dept Med, Sydney, NSW, Australia
[11] Mayo Clin, Dept Med Oncol, Rochesterd, MN USA
[12] Mayo Clin, Dept Hematol Oncol, Jacksonville, FL 32224 USA
[13] Gustave Roussy, Serv Dermatol, Dept Oncol, Villejuif, France
[14] Brigham & Womens Hosp, Med Oncol, 75 Francis St, Boston, MA 02115 USA
[15] Harvard Med Sch, Boston, MA 02115 USA
[16] Univ Sydney, Dept Med, Wollstonecraft, Australia
[17] Chaim Sheba Med Ctr, Div Oncol, Tel Hashomer, Israel
[18] Merck & Co Inc, Med Oncol, Kenilworth, NJ USA
来源：
ANNALS OF ONCOLOGY | 2020年 / 31卷
关键词：
D O I：
10.1016/j.annonc.2020.08.1262
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1139P
引用
收藏
页码：S762 / S763
页数：2
相关论文
共 50 条
  • [41] Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
    Kyte, Jon Amund
    Aamdal, Steinar
    Dueland, Svein
    Saeboe-Larsen, Stein
    Inderberg, Else Marit
    Madsbu, Ulf Erik
    Skovlund, Eva
    Gaudernack, Gustav
    Kvalheim, Gunnar
    ONCOIMMUNOLOGY, 2016, 5 (11):
  • [42] Long-Term Safety Outcomes of Rozanolixizumab Treatment in Patients with Generalized Myasthenia Gravis: A Pooled Analysis
    Vissing, John
    Grosskreutz, Julian
    Habib, Ali A.
    Utsugisawa, Kimiaki
    Vu, Tuan
    Grosskreutz, Julian
    Boehnlein, Marion
    Gayfieva, Maryam
    Greve, Bernhard
    Tarancon, Thais
    Woltering, Franz
    Il, Vera
    ANNALS OF NEUROLOGY, 2024, 96 : S265 - S265
  • [43] Estimating the percentage of patients with advanced melanoma achieving long-term survival with pembrolizumab (Pembro) treatment in KEYNOTE-006
    Blank, C.
    Ma, J.
    Grob, J. J.
    Larkin, J.
    Neyns, B.
    McNeil, C.
    Lotem, M.
    Richtig, E.
    Masucci, G.
    Petrella, T.
    Ribas, A.
    Wang, J.
    Ibrahim, N.
    Anderson, K. M.
    Arance, A.
    ANNALS OF ONCOLOGY, 2016, 27
  • [44] Long-term safety and tolerability of Apremilast in patients with psoriasis: pooled safety analysis of the ESTEEM 1 and 2 trials
    Foley, P.
    Reich, K.
    Papp, K.
    Gordon, K. B.
    Griffiths, C. E. M.
    Chimenti, S.
    Lopez-Estebaranz, J. L.
    Gottlieb, A. B.
    Shah, Kamal
    Hu, ChiaChi
    Day, Robert M.
    Paul, Carle
    AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2015, 56 : 37 - 37
  • [45] Clinical and genetic Predictors of long-term Outcome in Patients with locally advanced Rectal Cancer
    Leu, M.
    Riebeling, T.
    Droege, L. H.
    Schirmer, M.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2020, 196 (SUPPL 1) : S12 - S12
  • [46] Long-term clinical outcome of palliative pelvic exenteration in patients with advanced gynecological malignancies
    Fotopoulou, C.
    Neumann, U.
    Kraetschell, R.
    Weidemann, H.
    Lichtenegger, W.
    Sehouli, J.
    ONKOLOGIE, 2010, 33 : 118 - 119
  • [47] Copanlisib, a PI3K Inhibitor, Demonstrates a Favorable Long-Term Safety Profile in a Pooled Analysis of Patients with Hematologic Malignancies
    Zinzani, Pier Luigi
    Santoro, Armando
    Mollica, Luigina
    Leppa, Sirpa
    Follows, George A.
    Lenz, Georg
    Kim, Won Seog
    Nagler, Arnon
    Panayiotidis, Panayiotis
    Demeter, Judit
    Morschhauser, Franck
    Munoz, Javier
    Miriyala, Ashok
    Benson, Alice
    Garcia-Vargas, Jose
    Childs, Barrett H.
    Dreyling, Martin
    BLOOD, 2019, 134
  • [48] Quantifying the Long-term Survival Benefit of Pembrolizumab for Patients With Advanced Gastric Cancer
    Mccaw, Zachary R.
    Ludmir, Ethan B.
    Wei, Lee-Jen
    JAMA ONCOLOGY, 2021, 7 (04) : 632 - 633
  • [49] Analysis of Calculated Liver Scores for Long-Term Outcome in 423 Cutaneous Melanoma Patients
    Abu Rached, Nessr
    Reis, Mariana Marques da Silva
    Stockfleth, Eggert
    Kaepynen, Riina
    Gambichler, Thilo
    CANCERS, 2024, 16 (18)
  • [50] Correlation between baseline characteristics and clinical outcome of patients with advanced melanoma treated with pembrolizumab (PEMBRO)
    Jansen, Y.
    Rozeman, E. A.
    Hojberg, L.
    Foppen, M. Geukes
    Schreuer, M.
    van Thienen, J. V.
    Bastholt, L.
    Schmidt, H.
    Haanen, J. B. A. G.
    Svane, I. M.
    Arance Fernandez, A. M.
    Blank, C.
    Neyns, B.
    ANNALS OF ONCOLOGY, 2016, 27
12345