Principles of New DNA Sequencing Methods

被引:0
|
作者
Gaplovsky, Martin [1 ]
Gaplovska-Kysela, Katarina [2 ]
机构
[1] Comenius Univ, Fac Pharm, Dept Pharmaceut Chem, Bratislava 83104, Slovakia
[2] Comenius Univ, Fac Nat Sci, Dept Genet, Bratislava 84215, Slovakia
来源
CHEMICKE LISTY | 2012年 / 106卷 / 09期
关键词
HUMAN GENOME; SINGLE; MOLECULES; ELECTROPHORESIS; POLYMERASE; GENERATION; NANOPORE; IDENTIFICATION; FLUORESCENCE; LIMITATIONS;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Recently, a combination of biochemical, chemical, physical and engineering techniques enabled a substantial advancement of determination of primary structure of nucleic acids. New methods emerged that made DNA sequencing faster, less expensive and less labor-consuming. This review describes principles of the current and new sequencing methods as well as indicates directions of future development.
引用
收藏
页码:809 / 817
页数:9
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