Principles of New DNA Sequencing Methods

被引：0

作者：

Gaplovsky, Martin ^{[1
]}

Gaplovska-Kysela, Katarina ^{[2
]}

机构：

[1] Comenius Univ, Fac Pharm, Dept Pharmaceut Chem, Bratislava 83104, Slovakia

[2] Comenius Univ, Fac Nat Sci, Dept Genet, Bratislava 84215, Slovakia

来源：

CHEMICKE LISTY | 2012年 / 106卷 / 09期

关键词：

HUMAN GENOME; SINGLE; MOLECULES; ELECTROPHORESIS; POLYMERASE; GENERATION; NANOPORE; IDENTIFICATION; FLUORESCENCE; LIMITATIONS;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Recently, a combination of biochemical, chemical, physical and engineering techniques enabled a substantial advancement of determination of primary structure of nucleic acids. New methods emerged that made DNA sequencing faster, less expensive and less labor-consuming. This review describes principles of the current and new sequencing methods as well as indicates directions of future development.

引用

页码：809 / 817

页数：9

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