Staphylococcus lugdunensis, a coagulase-negative Staphylococcus species, is an increasingly relevant pathogen in the clinical setting. The organism has been isolated as a source of multiple clinical manifestations, including endocarditis. Herein, the authors present 2 cases of Staphylococcus lugdunensis endocarditis. These cases demonstrate the enhanced virulence and wide range of disease severity this organism creates. This enhanced virulence, undoubtedly present in these cases, led to novel daptomycin antibiotic regimen. To the best of the authors knowledge, these are the first reported cases using daptomycin in the treatment of Staphylococcus lugdunensis endocarditis.
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Brigham & Womens Hosp, Dept Surg, Boston, MA 02115 USABrigham & Womens Hosp, Dept Surg, Boston, MA 02115 USA
Cevasco, Marisa
Haime, Miguel
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Harvard Univ, Sch Med, W Roxbury, MA USA
VA Boston Healthcare Syst, Dept Cardiac Surg, W Roxbury, MA USABrigham & Womens Hosp, Dept Surg, Boston, MA 02115 USA
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Case Western Reserve Univ, Metrohealth Med Ctr, Dept Internal Med, Cleveland, OH 44109 USACase Western Reserve Univ, Metrohealth Med Ctr, Dept Internal Med, Cleveland, OH 44109 USA
Chopra, Anish
Gulati, Dhiraj
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Case Western Reserve Univ, Metrohealth Med Ctr, Dept Internal Med, Cleveland, OH 44109 USACase Western Reserve Univ, Metrohealth Med Ctr, Dept Internal Med, Cleveland, OH 44109 USA
Gulati, Dhiraj
Woldenberg, Nina
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Case Western Reserve Univ, Sch Med, Cleveland, OH USACase Western Reserve Univ, Metrohealth Med Ctr, Dept Internal Med, Cleveland, OH 44109 USA
Woldenberg, Nina
Singh, Mamta
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Case Western Reserve Univ, Dept Internal Med, Louis Stokes Cleveland VA Hosp, Cleveland, OH 44106 USACase Western Reserve Univ, Metrohealth Med Ctr, Dept Internal Med, Cleveland, OH 44109 USA
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United Christian Hosp, Div Cardiol, Kwun Tong, Hong Kong, Peoples R ChinaUnited Christian Hosp, Div Cardiol, Kwun Tong, Hong Kong, Peoples R China
Cheung, Ling Ling
Yue, Chiu Sun
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United Christian Hosp, Div Cardiol, Kwun Tong, Hong Kong, Peoples R ChinaUnited Christian Hosp, Div Cardiol, Kwun Tong, Hong Kong, Peoples R China
Yue, Chiu Sun
Fung, Kitty
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United Christian Hosp, Dept Pathol, Div Microbiol, Kwun Tong, Hong Kong, Peoples R ChinaUnited Christian Hosp, Div Cardiol, Kwun Tong, Hong Kong, Peoples R China
Fung, Kitty
Chu, Chung Ming
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United Christian Hosp, Div Resp Med, Kwun Tong, Hong Kong, Peoples R ChinaUnited Christian Hosp, Div Cardiol, Kwun Tong, Hong Kong, Peoples R China
Chu, Chung Ming
Tso, Eugene Yuk Keung
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United Christian Hosp, Dept Med & Geriatr, Div Infect Dis, Kwun Tong, Hong Kong, Peoples R ChinaUnited Christian Hosp, Div Cardiol, Kwun Tong, Hong Kong, Peoples R China