THE PRENYLATED CHALCONE XANTHOHUMOL INDUCES UNFOLDED PROTEIN RESPONSE, AUTOPHAGY, AND CELL DEATH IN BREAST CANCER CELLS BY PROTEASOME INHIBITION

被引：0
|
作者：
Vanhoecke, Barbara [1 ]
Van Gele, Mireille [2 ]
Martinet, Wim [5 ]
Vercoutter-Edouart, Anne-Sophie [6 ]
Lust, Sofie [3 ]
Debruyne, Delphine [1 ]
De Keukeleire, Denis [4 ]
Offner, Fritz [3 ]
Bracke, Marc [1 ]
机构：
[1] Ghent Univ Hosp, Lab Expt Canc Res, Dept Radiotherapy & Nucl Med, B-9000 Ghent, Belgium
[2] Ghent Univ Hosp, Dept Dermatol, B-9000 Ghent, Belgium
[3] Ghent Univ Hosp, Dept Hematol, B-9000 Ghent, Belgium
[4] Univ Ghent, Lab Pharmacognosy & Phytochem, B-9000 Ghent, Belgium
[5] Univ Antwerp, Div Pharmacol, B-2610 Antwerp, Belgium
[6] Univ Lille 1, F-59655 Villeneuve Dascq, France
来源：
ANTICANCER RESEARCH | 2008年 / 28卷 / 5C期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
693
引用
收藏
页码：3525 / 3526
页数：2
相关论文
共 50 条
  • [41] Chlorpromazine induces cytotoxic autophagy in glioblastoma cells via endoplasmic reticulum stress and unfolded protein response
    Matteoni, Silvia
    Matarrese, Paola
    Ascione, Barbara
    Ricci-Vitiani, Lucia
    Pallini, Roberto
    Villani, Veronica
    Pace, Andrea
    Paggi, Marco G.
    Abbruzzese, Claudia
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2021, 40 (01)
  • [42] Serine 129 phosphorylation of α-synuclein induces unfolded protein response-mediated cell death
    Sugeno, Naoto
    Takeda, Atsushi
    Hasegawa, Takafumi
    Kobayashi, Michiko
    Kikuchi, Akio
    Mori, Fumiaki
    Wakabayashi, Koichi
    Itoyama, Yasuto
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (34) : 23179 - 23188
  • [43] Inhibition of Autophagy Triggers Apoptotic Cell Death in Pancreatic Cancer Cells
    Mujumdar, N.
    MacKenzie, T.
    Vickers, S.
    Saluja, A.
    PANCREAS, 2009, 38 (08) : 1029 - 1029
  • [44] Serine 129 phosphorylation of α-synuclein induces unfolded protein response-mediated cell death
    Sugeno, N.
    Takeda, A.
    Kobayashi, M.
    Kikuchi, A.
    Hasegawa, T.
    Itoyama, Y.
    MOVEMENT DISORDERS, 2008, 23 (01) : S17 - S17
  • [45] Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy
    Okumura, Naoki
    Kitahara, Miu
    Okuda, Hirokazu
    Hashimoto, Keisuke
    Ueda, Emi
    Nakahara, Makiko
    Kinoshita, Shigeru
    Young, Robert D.
    Quantock, Andrew J.
    Tourtas, Theofilos
    Schloetzer-Schrehardt, Ursula
    Kruse, Friedrich
    Koizumi, Noriko
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2017, 58 (09) : 3697 - 3707
  • [46] Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent
    Sharma, Natasha
    Thomas, Simmy
    Golden, Encouse B.
    Hofman, Florence M.
    Chen, Thomas C.
    Petasis, Nicos A.
    Schoenthal, Axel H.
    Louie, Stan G.
    CANCER LETTERS, 2012, 326 (02) : 143 - 154
  • [47] VCP inhibition induces an unfolded protein response and apoptosis in human acute myeloid leukemia cells
    Szczesniak, Pawel P.
    Heidelberger, Jan B.
    Serve, Hubert
    Beli, Petra
    Wagner, Sebastian A.
    PLOS ONE, 2022, 17 (04):
  • [48] Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells
    Yucel Ustundag
    Steven F Bronk
    Gregory J Gores
    World Journal of Gastroenterology, 2007, (06) : 851 - 857
  • [49] A Nontoxic Concentration of Cisplatin Induces Autophagy in Cervical Cancer Selective Cancer Cell Death With Autophagy Inhibition as an Adjuvant Treatment
    Leisching, Gina
    Loos, Benjamin
    Botha, Matthys
    Engelbrecht, Anna-Mart
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2015, 25 (03) : 380 - 388
  • [50] Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells
    Ustundag, Yucel
    Bronk, Steven F.
    Gores, Gregory J.
    WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 13 (06) : 851 - 857
12345