Did a muscle fuel gauge conquer the brain?

被引：7

作者：

Pocai, A ^{[1
]}

Muse, ED

Rossetti, L

机构：

[1] Albert Einstein Coll Med, Diabet Res Ctr, Dept Med, Bronx, NY 10461 USA

[2] Albert Einstein Coll Med, Diabet Res Ctr, Dept Mol Pharmacol, Bronx, NY 10461 USA

来源：

NATURE MEDICINE | 2006年 / 12卷 / 01期

关键词：

D O I：

10.1038/nm0106-50

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

AMP-activated protein kinase has a crucial role in coupling substrate availability with substrate oxidation in skeletal muscle. Recent findings suggest that this biochecmical fuel sensor also participates in the hypothalmic recognition of the body's energy status.

引用

页码：50 / 51

页数：2

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