Advances in mechanisms of allergy and clinical immunology in 2012

被引:14
|
作者
Bochner, Bruce S. [1 ]
Rothenberg, Marc E. [2 ]
Boyce, Joshua A. [3 ]
Finkelman, Fred [2 ]
机构
[1] Johns Hopkins Univ, Sch Med, Div Allergy & Clin Immunol, Dept Med, Baltimore, MD USA
[2] Cincinnati Childrens Hosp Med Ctr, Div Allergy & Immunol, Dept Pediat, Cincinnati, OH USA
[3] Brigham & Womens Hosp, Dept Med, Div Rheumatol Immunol & Allergy, Boston, MA 02115 USA
基金
美国国家卫生研究院;
关键词
Dendritic cells; cytokines; immunotherapy; mast cell; basophil; eosinophil; T cells; regulatory T cells; THYMIC STROMAL LYMPHOPOIETIN; TOLEROGENIC DENDRITIC CELLS; REGULATORY T-CELLS; SUBLINGUAL IMMUNOTHERAPY; AIRWAY INFLAMMATION; T(H)2 CELLS; RECEPTOR; ASTHMA; SENSITIZATION; REACTIVITY;
D O I
10.1016/j.jaci.2012.12.676
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Manuscripts published in the "Mechanisms of allergy and clinical immunology" section of the Journal of Allergy and Clinical Immunology during 2012 enhanced our knowledge of the involvement of cytokines and other mediators in allergic disorders and described novel approaches for understanding mechanisms of allergic and immunologic diseases. Also published were articles focused on mechanisms of allergen-specific immunotherapy and the development of novel antiallergic treatments, as well as strategies to achieve tolerance to allergens. The highlights of these studies and their potential clinical implications are summarized in this review. (J Allergy Clin Immunol 2013;131:661-7.)
引用
收藏
页码:661 / 667
页数:7
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