iPSC-Derived Bronchospheres as a Novel Platform for Cystic Fibrosis Drug Development

被引:0
|
作者
Berical, A. [1 ]
Beermann, M. [1 ]
Thomas, D. C. [1 ]
Ranallo, N. [1 ]
McNally, P. G. [2 ]
Hurley, K. J. [3 ]
Randell, S. H. [4 ]
Kotton, D. N. [1 ]
Hawkins, F. J. [1 ]
机构
[1] Boston Univ, Sch Med, Ctr Regenerat Med, Boston, MA 02118 USA
[2] Royal Coll Surgeons Ireland, Paediat, Dublin, Ireland
[3] Royal Coll Surgeons Ireland, Resp, Dublin, Ireland
[4] Univ N Carolina, Marsico Lung Inst, Chapel Hill, NC USA
关键词
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A6197
引用
收藏
页数:2
相关论文
共 50 条
  • [41] DEVELOPMENT OF AN EBOLA VIRUS PATHOGENESIS MODEL USING IPSC-DERIVED HEPATOCYTES
    Manhart, Whitney
    Muhlberger, Elke
    Mostoslavsky, Gustavo
    GASTROENTEROLOGY, 2018, 154 (06) : S1081 - S1081
  • [42] Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration
    Gokul Ramaswami
    Yeliz Yuva-Aydemir
    Brynn Akerberg
    Bryan Matthews
    Jenna Williams
    Gabriel Golczer
    Jiaqi Huang
    Ali Al Abdullatif
    Dann Huh
    Linda C. Burkly
    Sandra J. Engle
    Iris Grossman
    Alfica Sehgal
    Alla A. Sigova
    Robert T. Fremeau
    Yuting Liu
    David Bumcrot
    Scientific Reports, 14
  • [43] A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids
    Boutin, Molly E.
    Strong, Caroline E.
    Van Hese, Brittney
    Hu, Xin
    Itkin, Zina
    Chen, Yu-Chi
    LaCroix, Andrew
    Gordon, Ryan
    Guicherit, Oivin
    Carromeu, Cassiano
    Kundu, Srikanya
    Lee, Emily
    Ferrer, Marc
    SLAS DISCOVERY, 2022, 27 (04) : 209 - 218
  • [44] Human iPSC-derived liver co-culture spheroids to model liver fibrosis
    Cools, Laura
    Dastjerd, Mina Kazemzadeh
    Smout, Ayla
    Merens, Vincent
    Yang, Yuwei
    Reynaert, Hendrik
    Messaoudi, Nouredin
    De Smet, Vincent
    Kumar, Manoj
    Verhulst, Stefaan
    Verfaillie, Catherine
    van Grunsven, Leo A.
    BIOFABRICATION, 2024, 16 (03)
  • [45] An Electrophysiological and Pharmacological Study of the Properties of Human iPSC-Derived Neurons for Drug Discovery
    Halliwell, Robert F.
    Salmanzadeh, Hamed
    Coyne, Leanne
    Cao, William S.
    CELLS, 2021, 10 (08)
  • [46] Development of a human iPSC-derived placental barrier-on-chip model
    Lermant, Agathe
    Rabussier, Gwenaelle
    Lanz, Henriette L.
    Davidson, Lindsay
    Porter, Iain M.
    Murdoch, Colin E.
    ISCIENCE, 2023, 26 (07)
  • [47] A human iPSC-derived CNS platform to investigate T cell autoreactivity in multiple sclerosis
    Perriot, S.
    Jones, S.
    Begarie, D.
    Canales, M.
    Oberholster, L.
    Theaudin, M.
    Pot, C.
    Mathias, A.
    Du Pasquier, R.
    MULTIPLE SCLEROSIS JOURNAL, 2021, 27 (2_SUPPL) : 359 - 360
  • [48] Utility of an in vitro platform to assess neuronal toxicity using human iPSC-derived neurons
    Misner, Dinah
    Snyder, Chelsea
    Ngo, Tin
    Yu, Lanlan
    Stagg, Nicola
    Staflin, Karin
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2016, 81 : 376 - 376
  • [49] Advancing Drug Discovery for Neurological Disorders Using iPSC-Derived Neural Organoids
    Costamagna, Gianluca
    Comi, Giacomo Pietro
    Corti, Stefania
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (05) : 1 - 21
  • [50] Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening
    Gutbier, Simon
    Wanke, Florian
    Dahm, Nadine
    Rummelin, Anna
    Zimmermann, Silke
    Christensen, Klaus
    Kochl, Fabian
    Rautanen, Anna
    Hatje, Klas
    Geering, Barbara
    Zhang, Jitao David
    Britschgi, Markus
    Cowley, Sally A.
    Patsch, Christoph
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (13) : 1 - 23