iPSC-Derived Bronchospheres as a Novel Platform for Cystic Fibrosis Drug Development

被引:0
|
作者
Berical, A. [1 ]
Beermann, M. [1 ]
Thomas, D. C. [1 ]
Ranallo, N. [1 ]
McNally, P. G. [2 ]
Hurley, K. J. [3 ]
Randell, S. H. [4 ]
Kotton, D. N. [1 ]
Hawkins, F. J. [1 ]
机构
[1] Boston Univ, Sch Med, Ctr Regenerat Med, Boston, MA 02118 USA
[2] Royal Coll Surgeons Ireland, Paediat, Dublin, Ireland
[3] Royal Coll Surgeons Ireland, Resp, Dublin, Ireland
[4] Univ N Carolina, Marsico Lung Inst, Chapel Hill, NC USA
关键词
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A6197
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Induced Pluripotent Stem Cell-Derived Bronchospheres as a Novel Platform for Personalized Cystic Fibrosis Drug Prediction
    Berical, A.
    McCauley, K. B.
    Thomas, D. C.
    Randell, S. H.
    Kotton, D. N.
    Hawkins, F.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2018, 197
  • [2] Personalized Drug Prediction For Cystic Fibrosis Using Ipsc-Derived Lung Organoids
    Hawkins, F. J.
    Thomas, D. C.
    McCauley, K. B.
    Crane, A.
    Davis, B.
    Kotton, D. N.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
  • [3] A multimodal iPSC platform for cystic fibrosis drug testing
    Berical, Andrew
    Lee, Rhianna E.
    Lu, Junjie
    Beermann, Mary Lou
    Le Suer, Jake A.
    Mithal, Aditya
    Thomas, Dylan
    Ranallo, Nicole
    Peasley, Megan
    Stuffer, Alex
    Bukis, Katherine
    Seymour, Rebecca
    Harrington, Jan
    Coote, Kevin
    Valley, Hillary
    Hurley, Killian
    McNally, Paul
    Mostoslavsky, Gustavo
    Mahoney, John
    Randell, Scott H.
    Hawkins, Finn J.
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [4] A multimodal iPSC platform for cystic fibrosis drug testing
    Andrew Berical
    Rhianna E. Lee
    Junjie Lu
    Mary Lou Beermann
    Jake A. Le Suer
    Aditya Mithal
    Dylan Thomas
    Nicole Ranallo
    Megan Peasley
    Alex Stuffer
    Katherine Bukis
    Rebecca Seymour
    Jan Harrington
    Kevin Coote
    Hillary Valley
    Killian Hurley
    Paul McNally
    Gustavo Mostoslavsky
    John Mahoney
    Scott H. Randell
    Finn J. Hawkins
    Nature Communications, 13
  • [5] iPSC-Derived Hepatocytes as a Platform for Disease Modeling and Drug Discovery
    Corbett, James L.
    Duncan, Stephen A.
    FRONTIERS IN MEDICINE, 2019, 6
  • [6] iPSC-derived macrophages from Cystic Fibrosis patients for infection models and drug screening platforms.
    Rodriguez-Gonzalez, C.
    Hashtchin, A. Rafiei
    Merkert, S.
    Munder, A.
    Lachmann, N.
    HUMAN GENE THERAPY, 2021, 32 (19-20) : A41 - A42
  • [7] An iPSC-derived drug screening platform to identify therapeutic compounds for marfan syndrome
    Mcnamara, M.
    Granata, A.
    Serrano, F.
    Bernard, W.
    Smith, D.
    Sanjay, S.
    CARDIOVASCULAR RESEARCH, 2018, 114 : S27 - S27
  • [8] A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients
    Jiang, Jia Xin
    Wellhauser, Leigh
    Laselva, Onofrio
    Utkina, Irina
    Bozoky, Zoltan
    Gunawardena, Tarini
    Ngan, Zoe
    Xia, Sunny
    Di Paola, Michelle
    Eckford, Paul D. W.
    Ratjen, Felix
    Moraes, Theo J.
    Parkinson, John
    Wong, Amy P.
    Bear, Christine E.
    STEM CELL REPORTS, 2021, 16 (11): : 2825 - 2837
  • [9] High throughput physiological screening of iPSC-derived cardiomyocytes for drug development
    del Alamo, Juan C.
    Lemons, Derek
    Serrano, Ricardo
    Savchenko, Alex
    Cerignoli, Fabio
    Bodmer, Rolf
    Mercola, Mark
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2016, 1863 (07): : 1717 - 1727
  • [10] Human iPSC-Derived Glia as a Tool for Neuropsychiatric Research and Drug Development
    Heider, Johanna
    Vogel, Sabrina
    Volkmer, Hansjuergen
    Breitmeyer, Ricarda
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (19)