Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues

被引:0
|
作者
Krimmel, Jeffrey D.
Schmitt, Michael W.
Kennedy, Scott R.
Harrell, Maribel I.
Agnew, Kathy J.
Loeb, Larry A.
Swisher, Elizabeth M.
Risques, Rosa Ana
机构
关键词
D O I
10.1158/1538-7445.AM2016-445
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
445
引用
收藏
页数:3
相关论文
共 43 条
  • [31] Targeted DNA sequencing of high-grade serous ovarian carcinoma reveals association of TP53 mutations with platinum resistance when combined with gene expression
    Holy, Petr
    Hlavac, Viktor
    Seborova, Karolina
    Susova, Simona
    Tesarova, Tereza
    Rob, Lukas
    Hruda, Martin
    Bouda, Jiri
    Bartakova, Alena
    Mrhalova, Marcela
    Kopeckova, Katerina
    Allah, Mohammad Al Obeed
    Spacek, Jiri
    Sedlakova, Iva
    Soucek, Pavel
    Vaclavikova, Radka
    INTERNATIONAL JOURNAL OF CANCER, 2024, 155 (01) : 104 - 116
  • [32] An Amplicon-Targeted Ultra-Deep Sequencing Approach Reveals the Presence at the Onset of Multiple Myeloma and the Selection over Time of TP53 Sub-Clonal Variants, Which Adversely Influence Patients' Overall Survival
    Terragna, Carolina
    Martello, Marina
    Procacci, Mauro
    Mignone, Flavio
    Pezzi, Annalisa
    Santacroce, Barbara
    Pantani, Lucia
    Saggese, Igor
    Haferlach, Torsten
    Zamagni, Elena
    Borsi, Enrica
    Tacchetti, Paola
    Zannetti, Beatrice A.
    Rocchi, Serena
    Mancuso, Katia
    Dico, Flores A.
    Martinelli, Giovanni
    Cavo, Michele
    BLOOD, 2015, 126 (23)
  • [33] Targeted Genomic Sequencing Reveals Novel TP53 In-frame Deletion Mutations Leading to p53 Overexpression in High-grade Serous Tubo-ovarian Carcinoma
    Jung, Yoon Yang
    Woo, Ha Young
    Kim, Hyun-Soo
    ANTICANCER RESEARCH, 2019, 39 (06) : 2883 - 2889
  • [34] Somatic Mutations of TP53 Identified by Targeted Next-Generation Sequencing Are Poor Prognostic Factors for Primary Operable Breast Cancer: A Single- Center Study
    Park, Jung Ho
    Kwon, Mi Jung
    Seo, Jinwon
    Kim, Ho Young
    Min, Soo Kee
    Kim, Lee Su
    JOURNAL OF BREAST CANCER, 2022, 25 (05) : 379 - 386
  • [35] Case Series of Somatic TP53 Mutations arising in Hematopoietic Cells Identified Incidentally During Multi-Gene Testing to Evaluate Germline Cancer Risk
    Konnick, E. Q.
    Leppig, K. A.
    Walsh, T. D.
    Keel, S.
    Garrett, L. T.
    Jacobson, A. L.
    King, M.
    Wu, D.
    Tait, J. F.
    Lockwood, C. M.
    Pritchard, C. C.
    Shirts, B. H.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2015, 17 (06): : 755 - 755
  • [36] Detecting TP53 mutations in diagnostic and archival liquid-based Pap samples from ovarian cancer patients using an ultra-sensitive ddPCR method
    Arildsen, Nicolai Skovbjerg
    de la Fuente, Laura Martin
    Masback, Anna
    Malander, Susanne
    Forslund, Ola
    Kannisto, Paivi
    Hedenfalk, Ingrid
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [37] Detecting TP53 mutations in diagnostic and archival liquid-based Pap samples from ovarian cancer patients using an ultra-sensitive ddPCR method
    Nicolai Skovbjerg Arildsen
    Laura Martin de la Fuente
    Anna Måsbäck
    Susanne Malander
    Ola Forslund
    Päivi Kannisto
    Ingrid Hedenfalk
    Scientific Reports, 9
  • [38] TP53 hot spot mutations in ovarian cancer: Selective resistance to microtubule stabilizing agents in monoclonal cells and comparison of clinical outcomes from The Cancer Genome Atlas data
    Seagle, Brandon-Luke L.
    Hofstteter, Gerda
    Yang, Chia-Ping
    Eng, Kevin
    Odunsi-Akanji, Oluwatosin
    Odunsi, Kunle
    Shahabi, Shohreh
    CANCER RESEARCH, 2015, 75
  • [39] TP53 somatic evolution in cervical liquid-based cytology and blood from individuals with and without ovarian cancer and BRCA1 or BRCA2 germline mutations
    Ghezelayagh, Talayeh S.
    Kohrn, Brendan F.
    Fredrickson, Jeanne
    Krimmel-Morrison, Jeffrey D.
    Latorre-Esteves, Elena
    Tee, Xin-Ray
    Radke, Marc R.
    Manhardt, Enna
    Norquist, Barbara M.
    Katz, Ronit
    Swisher, Elizabeth M.
    Risques, Rosa Ana
    ONCOGENE, 2024, 43 (31) : 2421 - 2430
  • [40] The G199X and V157fs mutations in the TP53 gene promote malignancy in serous ovarian cancer: an analysis using whole-exome sequencing
    Su, Dan
    Nie, Man
    Yue, Jun
    ANNALS OF TRANSLATIONAL MEDICINE, 2021, 9 (08)