The untranslated regions of genes from Trypanosoma cruzi:: perspectives for functional characterization of strains and isolates

被引：7
|
作者：
Brandao, Adeilton [1 ]
机构：
[1] Fiocruz MS, Inst Oswaldo Cruz, Dept Trop Med, BR-21045900 Rio De Janeiro, Brazil
来源：
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2006年 / 101卷 / 07期
关键词：
untranslated regions; genes; genomes; protozoa;
D O I：
10.1590/S0074-02762006000700011
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The sequencing of Trypanosoma cruzi genome has been completed and a great deal of information is now available. However, the organization of protozoa genomes is somewhat elusive and much effort must be applied to reveal all the information coded in the nucleotide sequences. Among the DNA segments that needs further investigation are the untranslated regions of genes. Many of the T. cruzi genes that were revealed by the genome sequencing lack information about the untranslated regions. In this paper some features of these untranslated segments as well as their applications in T. cruzi populations are discussed.
引用
收藏
页码：775 / 777
页数：3
相关论文
共 50 条
  • [41] Genetic Variation and Exchange in Trypanosoma cruzi Isolates from the United States
    Roellig, Dawn M.
    Savage, Mason Y.
    Fujita, A. Wendy
    Barnabe, Christian
    Tibayrenc, Michel
    Steurer, Frank J.
    Yabsley, Michael J.
    PLOS ONE, 2013, 8 (02):
  • [42] Molecular characterization of susceptible and naturally resistant strains of Trypanosoma cruzi to benznidazole and nifurtimox
    Murta, SMF
    Gazzinelli, RT
    Brener, Z
    Romanha, AJ
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1998, 93 (02) : 203 - 214
  • [43] Molecular characterization of Trypanosoma cruzi Mexican strains and their behavior in the mouse experimental model
    Gomez-Hernandez, Cesar
    Rezende-Oliveira, Karine
    Nogueira Nascentes, Gabriel Antonio
    Batista, Lara Rocha
    Kappel, Henrique Borges
    Martinez-Ibarra, Jose Alejandro
    Contreras, Francisco Trujillo
    Lages-Silva, Eliane
    Ramirez, Luis Eduardo
    REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 2011, 44 (06) : 684 - 690
  • [44] DNA FINGERPRINTING OF TRYPANOSOMA-CRUZI - A NEW TOOL FOR CHARACTERIZATION OF STRAINS AND CLONES
    MACEDO, AM
    MARTINS, MS
    CHIARI, E
    PENA, SDJ
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1992, 55 (1-2) : 147 - 153
  • [45] Genotype variation of Trypanosoma cruzi isolates from different Brazilian biomes
    Araujo, C. A. C.
    Waniek, P. J.
    Xavier, S. C. C.
    Jansen, A. M.
    EXPERIMENTAL PARASITOLOGY, 2011, 127 (01) : 308 - 312
  • [46] TRYPANOSOMATID ISOLATES FROM HONDURAS - DIFFERENTIATION BETWEEN TRYPANOSOMA-CRUZI AND TRYPANOSOMA-RANGELI
    ACOSTA, L
    ROMANHA, AJ
    COSENZA, H
    KRETTLI, AU
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1991, 44 (06): : 676 - 683
  • [47] TRYPANOSOMA-CRUZI - CHARACTERIZATION OF INVITRO AND INVIVO SYNTHESIZED POLYPEPTIDES FROM EPIMASTIGOTE FORMS OF DIFFERENT STRAINS
    CUMMINGS, LM
    COTRIM, PC
    DASILVEIRA, JF
    EXPERIMENTAL PARASITOLOGY, 1987, 64 (03) : 354 - 360
  • [48] CHARACTERIZATION OF PARAGUAYAN TRYPANOSOMA-CRUZI STRAINS ISOLATED FROM ACUTE PATIENTS OF CHAGAS-DISEASE
    ACOSTA, N
    MALDONADO, M
    SANABRIA, L
    YALUFF, G
    FUENTES, S
    TORRES, S
    FERREIRA, ME
    DEARIAS, AR
    SHOZAWA, T
    TROPICAL MEDICINE AND PARASITOLOGY, 1995, 46 (03): : 195 - 200
  • [49] Characterization of a lysosomal serine carboxypeptidase from Trypanosoma cruzi
    Parussini, F
    García, M
    Mucci, J
    Agüero, F
    Sánchez, D
    Hellman, U
    Åslund, L
    Cazzulo, JJ
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2003, 131 (01) : 11 - 23
  • [50] Structural characterization of NETNES glycopeptide from Trypanosoma cruzi
    Chiodi, Carla G.
    Verli, Hugo
    CARBOHYDRATE RESEARCH, 2013, 373 : 28 - 34
12345