Ca2+-Activated K+ Channel KCa3.1 Regulates Il-10 Expression in Regulatory T Cells at the Recovery Phase of Inflammatory Bowel Disease Model

被引:0
|
作者
Ohya, Susumu [1 ]
Matsui, Mild [1 ]
Kajikuri, Junko [1 ]
Endo, Kyoko [1 ]
Kito, Hiroaki [1 ]
机构
[1] Nagoya City Univ, Dept Pharmacol, Sch Med, Nagoya, Aichi, Japan
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
1192-Pos
引用
收藏
页码:246A / 246A
页数:1
相关论文
共 50 条
  • [41] Calcium-activated K+ channel KCa3.1 Plays a Pro-inflammatory Role in α-Synuclein Models of Parkinson's Disease
    Malovic, Emir
    Sarkar, Souvarish
    Hai Nguyen
    Singh, Vikrant
    Jin, Huajun
    Anantharam, Vellareddy
    Kanthasamy, Arthi
    Wulff, Heike
    Kanthasamy, Anumantha G.
    FASEB JOURNAL, 2019, 33
  • [42] The Intermediate-conductance Ca2+ -activated K+ Channel KCa3.1 Regulates Monocyte Adhesiveness to VCAM-1 and Macrophage Cholesterol Efflux
    Lemaitre, Vincent
    Filimban, Linda
    Miura, Hiroto
    CIRCULATION, 2012, 126 (21)
  • [43] Downregulation of the Ca2+-activated K+ channel K(Ca)3.1 by histone deacetylase inhibition in human breast cancer cells
    Ohya, Susumu
    Kanatsuka, Saki
    Hatano, Noriyuki
    Kito, Hiroaki
    Matsui, Azusa
    Fujimoto, Mayu
    Matsuba, Sayo
    Niwa, Satomi
    Zhan, Peng
    Suzuki, Takayoshi
    Muraki, Katsuhiko
    PHARMACOLOGY RESEARCH & PERSPECTIVES, 2016, 4 (02):
  • [44] The Ca2+-activated potassium channel KCa3.1 in the metastatic cascade of A549 non-small cell lung cancer cells
    Bulk, E.
    Waelte, M.
    Hofschroeer, V.
    Schwab, A.
    ACTA PHYSIOLOGICA, 2016, 216
  • [45] The phosphatidylinositol 3-phosphate phosphatase myotubularin-related protein 6 (MTMR6) is a negative regulator of the Ca2+-Activated K+ channel KCa3.1
    Srivastava, S
    Li, Z
    Lin, L
    Liu, GX
    Ko, K
    Coetzee, WA
    Skolnik, EY
    MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (09) : 3630 - 3638
  • [46] The intermediate conductance Ca2+-activated K plus channel KCa3.1 contributes to the diuretic and natriuretic effects of furosemide: insights from knockout mice
    Huang, D. Y.
    Heinen, C.
    Gao, H.
    Sausbier, U.
    Sausbier, M.
    Ruth, P.
    Osswald, H.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2008, 377 : 61 - 61
  • [47] Upregulation of KCa3.1 K+ channel in mesenteric lymph node CD4+ T lymphocytes from a mouse model of dextran sodium sulfate-induced inflammatory bowel disease
    Ohya, Susumu
    Fukuyo, Yuka
    Kito, Hiroaki
    Shibaoka, Rina
    Matsui, Miki
    Niguma, Hiroki
    Maeda, Yasuhiro
    Yamamura, Hisao
    Fujii, Masanori
    Kimura, Kazunori
    Imaizumi, Yuji
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2014, 306 (10): : G873 - G885
  • [48] Kca3.1 inhibition-induced activation of the JNK/c-Jun signaling pathway enhances IL-10 expression in peripherally-induced regulatory T cells
    Matsui, Miki
    Kajikuri, Junko
    Endo, Kyoko
    Kito, Hiroaki
    Ohya, Susumu
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2022, 148 (01) : 1 - 5
  • [49] Inhibition of Interleukin 10 Transcription through the SMAD2/3 Signaling Pathway by Ca2+-Activated K+ Channel KCa 3.1 Activation in Human T-Cell Lymphoma HuT-78 Cells
    Matsui, Miki
    Kajikuri, Junko
    Kito, Hiroaki
    Endo, Kyoko
    Hasegawa, Yuki
    Murate, Shinya
    Ohya, Susumu
    MOLECULAR PHARMACOLOGY, 2019, 95 (03) : 294 - 302
  • [50] NS6180, a new KCa3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease
    Strobaek, D.
    Brown, D. T.
    Jenkins, D. P.
    Chen, Y-J
    Coleman, N.
    Ando, Y.
    Chiu, P.
    Jorgensen, S.
    Demnitz, J.
    Wulff, H.
    Christophersen, P.
    BRITISH JOURNAL OF PHARMACOLOGY, 2013, 168 (02) : 432 - 444