Clinical translation of the GRPR antagonist [99mTc]Tc-maSSS-PEG2-RM26 for targeting prostate tumors

被引：0
|
作者：
Orlova, Anna [1 ]
Abouzayed, Ayman [1 ]
Rinne, Sara [1 ]
Lushnikova, Nadezhda [2 ]
Usynin, Evgeny [2 ]
Doroshenko, A. [2 ]
Borin, Jesper [3 ]
Sorensen, Jens [1 ]
Tolmachev, Vladimir [1 ]
Chernov, Vladimir [2 ]
Rybina, Anastasia [2 ]
机构：
[1] Uppsala Univ, Uppsala, Sweden
[2] Russian Acad Sci, Tomsk Natl Res Med Ctr, Moscow, Russia
[3] KTH Royal Inst Technol, Stockholm, Sweden
来源：
NUCLEAR MEDICINE AND BIOLOGY | 2022年 / 114卷
关键词：
D O I：
暂无
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
P-54
引用
收藏
页码：S58 / S58
页数：1
相关论文
共 49 条
  • [21] Phase I trial of gastrin releasing peptide receptor antagonist [99mTc]Tc-DB8 for SPECT imaging of GRPR expression in breast cancer
    Tolmachev, V.
    Bragina, O.
    Larkina, M.
    Varvashenya, R.
    Maina, T.
    Nock, B. A.
    Kanellopoulos, P.
    Orlova, A.
    Chernov, V.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 51 : S482 - S482
  • [22] Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26
    Mitran, Bogdan
    Rinne, Sara S.
    Konijnenberg, Mark W.
    Maina, Theodosia
    Nock, Berthold A.
    Altai, Mohamed
    Vorobyeva, Anzhelika
    Larhed, Mats
    Tolmachev, Vladimir
    de Jong, Marion
    Rosenstrom, Ulrika
    Orlova, Anna
    INTERNATIONAL JOURNAL OF CANCER, 2019, 145 (12) : 3347 - 3358
  • [23] GRPR-Targeted Radiotherapy: Influence of Chelator on Labeling and Biodistribution of Four 177Lu-Labeled Analogues of the GRPR-Antagonist PEG2-RM26
    Orlova, A.
    Mitran, B.
    Maina, T.
    Nock, B. A.
    Rinne, S. S.
    Tolmachev, V.
    Rosenstrom, U.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 44 : S295 - S296
  • [24] Synthesis and evaluation of a 99mTc tricarbonyl-labeled somatostatin receptor-targeting antagonist peptide for imaging of neuroendocrine tumors
    Radford, Lauren
    Gallazzi, Fabio
    Watkinson, Lisa
    Carmack, Terry
    Berendzen, Ashley
    Lewis, Michael R.
    Jurisson, Silvia S.
    Papagiannopoulou, Dionysia
    Hennkens, Heather M.
    NUCLEAR MEDICINE AND BIOLOGY, 2017, 47 : 4 - 9
  • [25] Imaging and dosimetry of 99mTc EC annexin V:: Preliminary clinical study targeting apoptosis in breast tumors
    Kurihara, Hiroaki
    Yang, David J.
    Cristofanilli, Massimo
    Erwin, William D.
    Yu, Dong-Fang
    Kohanim, Saady
    Mendez, Richard
    Kim, E. Edmund
    APPLIED RADIATION AND ISOTOPES, 2008, 66 (09) : 1175 - 1182
  • [26] Dosimetry from the first-in-human study on [68Ga]GaNOTA-PEG 2-RM26-A GRPR antagonist
    Bjareback, A.
    Tzortzakakis, A.
    Estenberg, U.
    Axelsson, R.
    Jonmarker, O.
    Altena, R.
    Li, C.
    Moein, M.
    Orlova, A.
    Tran, T. A.
    Hindorf, C.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 51 : S803 - S803
  • [27] First-in-human experience with GRPR antagonist [68Ga]Ga-NOTA-PEG2-RM26 in prostate and breast cancer patients using PET/CT
    Bjareback, Annie
    Jonmarker, Olof
    Tzortzakakis, Antonios
    Jussing, Emma
    Li, Chunde
    Altena, Renske
    Hindorf, Cecilia
    Orlova, Anna
    Axelsson, Rimma
    Tran, Thuy A.
    EJNMMI RESEARCH, 2025, 15 (01):
  • [28] Direct clinical comparison of scaffold proteins [99mTc]Tc-ADAPT6 and [99mTc]Tc-(HE)3-G3 for imaging of HER2-positive breast cancer
    Tolmachev, Vladimir
    Bragina, Olga
    Schulga, Alexey
    Hober, Sophia
    Borin, Jesper
    Deyev, Sergey
    Chernov, Vladimir
    NUCLEAR MEDICINE AND BIOLOGY, 2023, 126 : S155 - S155
  • [29] One Step Closer to Clinical Translation: Enhanced Tumor Targeting of [99mTc]Tc-DB4 and [111In]In-SG4 in Mice Treated with Entresto
    Kanellopoulos, Panagiotis
    Kaloudi, Aikaterini
    Rouchota, Maritina
    Loudos, George
    de Jong, Marion
    Krenning, Eric P.
    Nock, Berthold A.
    Maina, Theodosia
    PHARMACEUTICS, 2020, 12 (12) : 1 - 14
  • [30] A heterodimeric [RGD-Glu-[64Cu-NO2A]-6-Ahx-RM2] αvβ3/GRPr-targeting antagonist radiotracer for PET imaging of prostate tumors
    Durkan, Kubra
    Jiang, Zongrun
    Rold, Tammy L.
    Sieckman, Gary L.
    Hoffman, Timothy J.
    Bandari, Rajendra Prasad
    Szczodroski, Ashley F.
    Liu, Liqin
    Miao, Yubin
    Reynolds, Tamila Stott
    Smith, Charles J.
    NUCLEAR MEDICINE AND BIOLOGY, 2014, 41 (02) : 133 - 139
12345