Alternative lengthening of telomeres is not synonymous with mutations in ATRX/DAXX

被引:27
|
作者
de Nonneville, Alexandre [1 ,2 ]
Reddel, Roger R. [1 ]
机构
[1] Univ Sydney, Fac Med & Hlth, Childrens Med Res Inst, Canc Res Unit, Westmead, NSW, Australia
[2] Aix Marseille Univ, CNRS, INSERM, Inst Paoli Calmettes,CRCM, Marseille, France
基金
瑞士国家科学基金会;
关键词
D O I
10.1038/s41467-021-21794-0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页数:4
相关论文
共 50 条
  • [31] Alternative lengthening of telomeres, ATRX loss and H3 p.K27M mutations in Anaplastic Pilocytic Astrocytoma
    Rodriguez, Fausto
    Brosnan-Cashman, Jacqueline
    Villalobos, Maria Adelita Vizcaino
    Giannini, Caterina
    Camelo-Piragua, Sandra
    Webb, Milad
    Matsushita, Marcus
    Wadhwani, Nitin
    Tabbarah, Abeer
    Rodriguez-Velasco, Alicia
    Heaphy, Christopher M.
    LABORATORY INVESTIGATION, 2018, 98 : 665 - 666
  • [32] Alternative lengthening of telomeres, ATRX loss and H3-K27M mutations in histologically defined pilocytic astrocytoma with anaplasia
    Rodriguez, Fausto J.
    Brosnan-Cashman, Jacqueline A.
    Allen, Sariah J.
    Vizcaino, M. Adelita
    Giannini, Caterina
    Camelo-Piragua, Sandra
    Webb, Milad
    Matsushita, Marcus
    Wadhwani, Nitin
    Tabbarah, Abeer
    Hamideh, Dima
    Jiang, Liqun
    Chen, Liam
    Arvanitis, Leonidas D.
    Alnajar, Hussein H.
    Barber, John R.
    Rodriguez-Velasco, Alicia
    Orr, Brent
    Heaphy, Christopher M.
    BRAIN PATHOLOGY, 2019, 29 (01) : 126 - 140
  • [33] Alternative lengthening of telomeres, ATRX loss and H3 p.K27M mutations in Anaplastic Pilocytic Astrocytoma
    Rodriguez, Fausto
    Brosnan-Cashman, Jacqueline
    Villalobos, Maria Adelita Vizcaino
    Giannini, Caterina
    Camelo-Piragua, Sandra
    Webb, Milad
    Matsushita, Marcus
    Wadhwani, Nitin
    Tabbarah, Abeer
    Rodriguez-Velasco, Alicia
    Heaphy, Christopher M.
    MODERN PATHOLOGY, 2018, 31 : 665 - 666
  • [34] Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors
    de Wilde, Roeland F.
    Heaphy, Christopher M.
    Maitra, Anirban
    Meeker, Alan K.
    Edil, Barish H.
    Wolfgang, Christopher L.
    Ellison, Trevor A.
    Schulick, Richard D.
    Molenaar, I. Quintus
    Valk, Gerlof D.
    Vriens, Menno R.
    Rinkes, Inne H. M. Borel
    Offerhaus, G. Johan A.
    Hruban, Ralph H.
    Matsukuma, Karen E.
    MODERN PATHOLOGY, 2012, 25 (07) : 1033 - 1039
  • [35] Mechanisms of Alternative Lengthening of Telomeres
    O'Sullivan, Roderick J.
    Greenberg, Roger A.
    COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2025, 17 (01):
  • [36] Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
    Lovejoy, Courtney A.
    Li, Wendi
    Reisenweber, Steven
    Thongthip, Supawat
    Bruno, Joanne
    de Lange, Titia
    De, Saurav
    Petrini, John H. J.
    Sung, Patricia A.
    Jasin, Maria
    Rosenbluh, Joseph
    Zwang, Yaara
    Weir, Barbara A.
    Hatton, Charlie
    Ivanova, Elena
    Macconaill, Laura
    Hanna, Megan
    Hahn, William C.
    Lue, Neal F.
    Reddel, Roger R.
    Jiao, Yuchen
    Kinzler, Kenneth
    Vogelstein, Bert
    Papadopoulos, Nickolas
    Meeker, Alan K.
    PLOS GENETICS, 2012, 8 (07):
  • [37] Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size
    Hackeng, Wenzel M.
    Brosens, Lodewijk A. A.
    Kim, Joo Young
    O'Sullivan, Roderick
    Sung, You-Na
    Liu, Ta-Chiang
    Cao, Dengfeng
    Heayn, Michelle
    Brosnan-Cashman, Jacqueline
    An, Soyeon
    Morsink, Folkert H. M.
    Heidsma, Charlotte M.
    Valk, Gerlof D.
    Vriens, Menno R.
    van Dijkum, Els Nieveen
    Offerhaus, G. Johan A.
    Dreijerink, Koen M. A.
    Zeh, Herbert
    Zureikat, Amer H.
    Hogg, Melissa
    Lee, Kenneth
    Geller, David
    Marsh, J. Wallis
    Paniccia, Alessandro
    Ongchin, Melanie
    Pingpank, James F.
    Bahary, Nathan
    Aijazi, Muaz
    Brand, Randall
    Chennat, Jennifer
    Das, Rohit
    Fasanella, Kenneth E.
    Khalid, Asif
    McGrath, Kevin
    Sarkaria, Savreet
    Singh, Harkirat
    Slivka, Adam
    Nalesnik, Michael
    Han, Xiaoli
    Nikiforova, Marina N.
    Lawlor, Rita Teresa
    Mafficini, Andrea
    Rusev, Boris
    Corbo, Vincenzo
    Luchini, Claudio
    Bersani, Samantha
    Pea, Antonio
    Cingarlini, Sara
    Landoni, Luca
    Salvia, Roberto
    GUT, 2022, 71 (05) : 961 - 973
  • [38] MOLECULAR BIOMARKERS ASSOCIATED WITH TARGETED DISRUPTION OF ALTERNATIVE LENGTHENING OF TELOMERES IN ATRX-DEFICIENT GLIOMA MODELS
    Waitkus, Matthew
    Brown, Michael
    Pirozzi, Christopher
    Reynolds, Nathan
    Brown, Alexandrea
    Strickland, Laura
    Reitman, Zachary
    Keir, Steve
    Khasraw, Mustafa
    Ashley, David
    NEURO-ONCOLOGY, 2023, 25
  • [39] Evaluation of chromatin remodeling factors ATRX and DAXX and telomeres in pediatric adrenocortical tumors
    Stecchini, Monica F.
    Bueno, Ana Carolina
    de Campos, Mateus R.
    Marrero-Gutierrez, Junier
    Cardinalli, Izilda A.
    Junqueira, Tais
    Scridelli, Carlos A.
    Molina, Carlos A. F.
    Tucci, Silvio
    Coeli-Lacchini, Fernanda B.
    Moreira, Ayrton C.
    Ramalho, Fernando S.
    Ramalho, Leandra N. Z.
    Brandalise, Silvia R.
    Yunes, Jose A.
    Chahud, Fernando
    Vencio, Ricardo Z. N.
    de Castro, Margaret
    Antonini, Sonir R.
    HORMONE RESEARCH IN PAEDIATRICS, 2023, 96 : 143 - 143
  • [40] A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas
    Henson, JD
    Hannay, JA
    McCarthy, SW
    Royds, JA
    Yeager, TR
    Robinson, RA
    Wharton, SB
    Jellinek, DA
    Arbuckle, SM
    Yoo, JY
    Robinson, BG
    Learoyd, DL
    Stalley, PD
    Bonar, SF
    Yu, DH
    Pollock, RE
    Reddel, RR
    CLINICAL CANCER RESEARCH, 2005, 11 (01) : 217 - 225