Extraesophageal Manifestations of Gastroesophageal Reflux Disease

被引:40
|
作者
Hom, Christopher [1 ]
Vaezi, Michael F. [1 ]
机构
[1] Vanderbilt Univ, Med Ctr, Div Gastroenterol Hepatol & Nutr, Ctr Swallowing & Esophageal Disorders, Nashville, TN 37232 USA
关键词
Extraesophageal reflux syndrome; Laryngopharyngeal reflux; Chronic laryngitis; Asthma; Chronic cough; MULTICHANNEL INTRALUMINAL IMPEDANCE; LARYNGEAL SENSORY NEUROPATHY; PLACEBO-CONTROLLED CROSSOVER; POORLY CONTROLLED ASTHMA; CHRONIC COUGH; DOUBLE-BLIND; LARYNGOPHARYNGEAL REFLUX; CONTROLLED-TRIAL; UNITED-STATES; ACID REFLUX;
D O I
10.1016/j.gtc.2012.11.004
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
This article discusses the current state of knowledge regarding the relationship between gastroesophageal reflux disease (GERD) and pulmonary and ear/nose/throat manifestations of reflux and outlines the recent developments in the diagnostic and treatment strategies for this difficult group of patients. Upper gastrointestinal endoscopy and pH monitoring are poorly sensitive for diagnosing reflux in this group of patients. Instead it is recommended that in those without warning symptoms, an empiric trial of proton-pump inhibitors be the initial approach to diagnosing and treating the potential underlying cause of these extraesophageal symptoms.
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页码:71 / +
页数:22
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