TOPOISOMERASE II IS OVEREXPRESSED IN GLIOBLASTOMA AND IS A POTENTIALLY USEFUL PREDICTOR OF ETOPOSIDE SENSITIVITY

被引:0
|
作者
Parkinson, Jonathon [1 ]
Shaw, Janet [1 ]
Payne, Cathy
Brewer, Janice [2 ]
Wheeler, Helen [3 ]
Cook, Raymond [4 ]
Biggs, Michael [4 ]
Little, Nicholas [4 ]
Teo, Charles [5 ]
Messina, Marinella
Rohinson, Bruce
Mcdonald, Kerrie
机构
[1] Royal N Shore Hosp, Kolling Inst Med Res, Hormones & Canc Grp, St Leonards, NSW 2065, Australia
[2] Royal N Shore Hosp, Dept Anat Pathol, St Leonards, NSW, Australia
[3] Royal N Shore Hosp, Dept Oncol, St Leonards, NSW 2065, Australia
[4] Royal N Shore Hosp, Dept Neurosurg, St Leonards, NSW, Australia
[5] Prince Wales Hosp, Ctr Minimally Invas Neurosurg, Sydney, NSW, Australia
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:863 / 863
页数:1
相关论文
共 50 条
  • [41] MICRONUCLEI IN NEONATAL LYMPHOCYTES TREATED WITH THE TOPOISOMERASE-II INHIBITORS AMSACRINE AND ETOPOSIDE
    SLAVOTINEK, A
    PERRY, PE
    SUMNER, AT
    MUTATION RESEARCH, 1993, 319 (03): : 215 - 222
  • [42] A two-drug model for etoposide action against human topoisomerase IIα
    Bromberg, KD
    Burgin, AB
    Osheroff, N
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (09) : 7406 - 7412
  • [43] Analysis of etoposide binding to subdomains of human DNA topoisomerase IIα in the absence of DNA
    Leroy, D
    Kajava, AV
    Frei, C
    Gasser, SM
    BIOCHEMISTRY, 2001, 40 (06) : 1624 - 1634
  • [44] Effect of the topoisomerase-II inhibitor etoposide on meiotic recombination in male mice
    Russell, LB
    Hunsicker, PR
    Hack, AM
    Ashley, T
    MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2000, 464 (02) : 201 - 212
  • [45] Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis
    Johnson, CA
    Padget, K
    Austin, CA
    Turner, BM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (07) : 4539 - 4542
  • [46] YEAST TOPOISOMERASE-II MUTANTS RESISTANT TO ANTI-TOPOISOMERASE AGENTS - IDENTIFICATION AND CHARACTERIZATION OF NEW YEAST TOPOISOMERASE-II MUTANTS SELECTED FOR RESISTANCE TO ETOPOSIDE
    LIU, YX
    HSIUNG, YC
    JANNATIPOUR, M
    YEH, Y
    NITISS, JL
    CANCER RESEARCH, 1994, 54 (11) : 2943 - 2951
  • [47] Ectopic expression of human topoisomerase IIα fragments and etoposide resistance in mammalian cells
    Ernst, AI
    Soltermann, A
    Sigrist, JA
    Widmer, L
    Gasser, SM
    Stahel, RA
    INTERNATIONAL JOURNAL OF CANCER, 2000, 88 (01) : 99 - 107
  • [48] Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide
    N Hajji
    K Wallenborg
    P Vlachos
    J Füllgrabe
    O Hermanson
    B Joseph
    Oncogene, 2010, 29 : 2192 - 2204
  • [49] Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide
    Hajji, N.
    Wallenborg, K.
    Vlachos, P.
    Fullgrabe, J.
    Hermanson, O.
    Joseph, B.
    ONCOGENE, 2010, 29 (15) : 2192 - 2204
  • [50] Adenovirus-mediated human Topoisomerase IIα gene transfer increases the sensitivity of etoposide-resistant human breast cancer cells
    Zhou, ZC
    Zwelling, LA
    Kawakami, Y
    An, TH
    Kobayashi, K
    Herzog, C
    Kleinerman, ES
    CANCER RESEARCH, 1999, 59 (18) : 4618 - 4624