HLA class II DRB1 polymorphism in Argentinians undergoing chronic Trypanosoma cruzi infection

被引：8
|
作者：
Borrás, Silvia García
Diez, Cristina
Cotorruelo, Carlos
Pellizon, Oscar
Biondi, Claudia
Beloscar, Juan
Bottasso, Oscar
Racca, Amelia
机构：
[1] Univ Nacl Rosario, Fac Ciencias Bioquim & Farmaceut, RA-2000 Rosario, Santa Fe, Argentina
[2] Univ Nacl Rosario, Fac Ciencias Med, RA-2000 Rosario, Santa Fe, Argentina
[3] Univ Nacl Litoral, Fac Bioquim & Ciencias Biol, Santa Fe, Argentina
来源：
ANNALS OF CLINICAL BIOCHEMISTRY | 2006年 / 43卷
关键词：
D O I：
10.1258/000456306776865205
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
DNA typing of human lymphocyte antigen (HLA)-dicloro-1-[beta]-D-ribofuranosyl-benzimidazole 1 (DRB1) alleles in 35 individuals serologically positive for T cruzi and in 41 healthy controls was performed. DRB1*0409 allele was significantly more prevalent in seropositive individuals, with a trend being also observed for the DRB1*0701 and DRB1*1503 alleles. Although statistically insignificant, the latter was found more frequent in cases with cardiomyopathy.
引用
收藏
页码：214 / 216
页数：3
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