Obesity and Type 2 Diabetes are Associated with an Increased Risk of Developing Cancer and a Worse Prognosis; Epidemiological and Mechanistic Evidence

被引：100
|
作者：
LeRoith, D.
Novosyadlyy, R.
Gallagher, E. J.
Lann, D.
Vijayakumar, A.
Yakar, S.
机构：
[1] Division of Endocrinology and Diabetes, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029-6574, One Gustave L. Levy Place
来源：
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES | 2008年 / 116卷
关键词：
diabetes; obesity; cancer; epidemiology;
D O I：
10.1055/s-2008-1081488
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Both obesity and Type 2 diabetes are independently associated with an increased risk of developing cancer and an increased mortality. The etiology is yet to be determined but insulin resistance and hyperinsulinemia maybe important factors. Hyperglycemia, hyperlipidemia and inflammatory cytokines in addition to the insulin-like growth factors are also possible factors involved in the process.
引用
收藏
页码：S4 / S6
页数：3
相关论文
共 50 条
  • [31] Cardiometabolic Risk Factors Associated With Type 2 Diabetes Mellitus: A Mechanistic Insight
    Chakraborty, Snigdha
    Verma, Anjali
    Garg, Rajeev
    Singh, Jyoti
    Verma, Hitesh
    CLINICAL MEDICINE INSIGHTS-ENDOCRINOLOGY AND DIABETES, 2023, 16
  • [32] Unraveling the relationship between diabetes, obesity, and cancer from clinical, epidemiological, and mechanistic perspectives
    Goto, Atsushi
    Watada, Hirotaka
    CANCER SCIENCE, 2023, 114 : 975 - 975
  • [33] Effect of citrus fruit and juice consumption on risk of developing type 2 diabetes: Evidence on polyphenols from epidemiological and intervention studies
    Visvanathan, Rizliya
    Williamson, Gary
    TRENDS IN FOOD SCIENCE & TECHNOLOGY, 2021, 115 : 133 - 146
  • [34] Increased Kremen2 predicts worse prognosis in colon cancer
    Long, Junxian
    Cong, Fengyun
    Wei, Yousheng
    Liu, Jungang
    Tang, Weizhong
    PATHOLOGY & ONCOLOGY RESEARCH, 2023, 29
  • [35] Increased liver markers are associated with higher risk of type 2 diabetes
    Ko, Sun-Hye
    Baeg, Myong Ki
    Han, Kyung-Do
    Ko, Seung-Hyun
    Ahn, Yu-Bae
    WORLD JOURNAL OF GASTROENTEROLOGY, 2015, 21 (24) : 7478 - 7487
  • [36] Are antihypertensive drugs associated with an increased risk of incident type 2 diabetes?
    Pantelis A Sarafidis
    George L Bakris
    Nature Clinical Practice Endocrinology & Metabolism, 2007, 3 : 8 - 9
  • [37] Are antihypertensive drugs associated with an increased risk of incident type 2 diabetes?
    Sarafidis, Pantelis A.
    Bakris, George L.
    NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM, 2007, 3 (01): : 8 - 9
  • [38] Frailty Is Associated with an Increased Risk of Incident Type 2 Diabetes in the Elderly
    Veronese, Nicola
    Stubbs, Brendon
    Fontana, Luigi
    Trevisan, Caterina
    Bolzetta, Francesco
    De Rui, Marina
    Sartori, Leonardo
    Musacchio, Estella
    Zambon, Sabina
    Maggi, Stefania
    Perissinotto, Egle
    Corti, Maria Chiara
    Crepaldi, Gaetano
    Manzato, Enzo
    Sergi, Giuseppe
    JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2016, 17 (10) : 902 - 907
  • [39] Insomnia Is Associated with an Increased Risk of Type 2 Diabetes in the Clinical Setting
    Leblanc, Erin
    Smith, Ning
    Allison, Michael
    Nichols, Gregory
    Clarke, Greg
    DIABETES, 2018, 67
  • [40] Increased liver markers are associated with higher risk of type 2 diabetes
    Sun-Hye Ko
    Myong Ki Baeg
    Kyung-Do Han
    Seung-Hyun Ko
    Yu-Bae Ahn
    World Journal of Gastroenterology, 2015, 21 (24) : 7478 - 7487
12345