Whole-genome sequencing of East Asian lung cancers reveals new germline pathogenic variants

被引：1387
|
作者：
Mukherjee, Semanti [1 ,2 ]
Carrot-Zhang, Jian [1 ,3 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10065 USA
[2] Weill Cornell Med Coll, Dept Med, New York, NY USA
[3] Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, New York, NY 10065 USA
来源：
CANCER CELL | 2022年 / 40卷 / 10期
关键词：
METABOLISM;
D O I：
10.1016/j.immuni.2015.02.005
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In this issue of Cancer Cell, Wang et al. use whole-genome sequencing of lung cancer cases and controls with East Asian ancestry to comprehensively characterize both common and rare variants that predispose to lung cancer. Their findings suggest that rare promoter variants in BRCA2 are associated with increased lung can-cer risk.
引用
收藏
页码：1081 / 1083
页数：3
相关论文
共 50 条
  • [21] Whole-genome and transcriptome sequencing of 1063 colorectal cancers reveals novel drivers and prognostic subgroups
    Nunes, Luis
    Li, Fuqiang
    Hammarstrom, Klara
    Wu, Meizhen
    Lundin, Emma
    Luo, Tian
    Mezheyeuski, Artur
    Ljuslinder, Ingrid
    Mathot, Lucy
    Yacoub, Nicole
    Lofgren-Burstrom, Anna
    Zingmark, Carl
    Edqvist, Per-Henrik
    Neves, Ines
    Gudnadottir, Unnur
    Osterman, Erik
    Denes, Anna-Maria
    Larsson, Chatarina
    Ponten, Frederik
    Palmqvist, Richard
    Wu, Kui
    Lin, Cong
    Uhlen, Mathias
    Glimelius, Bengt
    Sjoblom, Tobias
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2023, 31 : 48 - 49
  • [22] Diagnostic rate of germline pathogenic variants in pancreatic ductal adenocarcinoma patients using whole genome sequencing
    Chung, An-Ko
    Lin, Ro-Ting
    Yeh, Chun-Chieh
    Yang, Chi-Ying
    Wu, Chang-Jiun
    Chen, Pei-Lung
    Lin, Jaw-Town
    FRONTIERS IN GENETICS, 2023, 14
  • [23] The most frequent germline pathogenic variants in Russian patients with breast cancer: whole genome sequencing results
    Makarova, Maria
    Nemtsova, Marina
    Byakhova, Maria
    Danishevich, Anastasia
    Chernevskiy, Denis
    Sagaidak, Olesya
    Vorontsova, Maria
    Belenikin, Maxim
    Krinitsina, Anastasia
    Antonenko, Aleksey
    Semenova, Anna
    Bodunova, Natalia
    Khatkov, Igor
    Galkin, Vsevolod
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2024, 32 : 919 - 919
  • [24] Genetic epidemiology of pharmacogenetic variants in South East Asian Malays using whole-genome sequences
    Sivadas, A.
    Salleh, M. Z.
    Teh, L. K. y
    Scaria, V.
    PHARMACOGENOMICS JOURNAL, 2017, 17 (05): : 461 - 470
  • [25] Genetic epidemiology of pharmacogenetic variants in South East Asian Malays using whole-genome sequences
    A Sivadas
    M Z Salleh
    L K Teh
    V Scaria
    The Pharmacogenomics Journal, 2017, 17 : 461 - 470
  • [26] Germline whole-exome sequencing of patients with neuroendocrine neoplasms reveals pathogenic or likely pathogenic variants in a large subset of patients
    Sukrithan, V
    Boateng, I
    Jain, P.
    Liyanarachchi, S.
    Buss, J.
    Parwani, A.
    Shah, M.
    Konda, B.
    Brock, P.
    Eisfeld, A. K.
    JOURNAL OF NEUROENDOCRINOLOGY, 2023, 35 : 36 - 36
  • [27] Whole-genome sequencing of Asian lung cancers: Second-hand smoke unlikely to be responsible for higher incidence of lung cancer among Asian never-smokers
    Hillmer, A.
    Krishnan, V. G.
    Ebert, P. J.
    Ting, J. C.
    Lim, E.
    Wong, S. S.
    Nilsen, G. B.
    Barber, T. D.
    Tan, P.
    Ng, P. C.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S113 - S113
  • [28] Whole-Genome Sequencing of Asian Lung Cancers: Second-Hand Smoke Unlikely to Be Responsible for Higher Incidence of Lung Cancer among Asian Never-Smokers
    Krishnan, Vidhya G.
    Ebert, Philip J.
    Ting, Jason C.
    Lim, Elaine
    Wong, Swee-Seong
    Teo, Audrey S. M.
    Yue, Yong G.
    Chua, Hui-Hoon
    Ma, Xiwen
    Loh, Gary S. L.
    Lin, Yuhao
    Tan, Joanna H. J.
    Yu, Kun
    Zhang, Shenli
    Reinhard, Christoph
    Tan, Daniel S. W.
    Peters, Brock A.
    Lincoln, Stephen E.
    Ballinger, Dennis G.
    Laramie, Jason M.
    Nilsen, Geoffrey B.
    Barber, Thomas D.
    Tan, Patrick
    Hillmer, Axel M.
    Ng, Pauline C.
    CANCER RESEARCH, 2014, 74 (21) : 6071 - 6081
  • [29] Whole-Genome Sequencing of Pathogenic Bacteria-New Insights into Antibiotic Resistance Spreading
    Shelenkov, Andrey
    MICROORGANISMS, 2021, 9 (12)
  • [30] Deep Whole-Genome Sequencing of 100 Southeast Asian Malays
    Wong, Lai-Ping
    Ong, Rick Twee-Hee
    Poh, Wan-Ting
    Liu, Xuanyao
    Chen, Peng
    Li, Ruoying
    Lam, Kevin Koi-Yau
    Pillai, Nisha Esakimuthu
    Sim, Kar-Seng
    Xu, Haiyan
    Sim, Ngak-Leng
    Teo, Shu-Mei
    Foo, Jia-Nee
    Tan, Linda Wei-Lin
    Lim, Yenly
    Koo, Seok-Hwee
    Gan, Linda Seo-Hwee
    Cheng, Ching-Yu
    Wee, Sharon
    Yap, Eric Peng-Huat
    Ng, Pauline Crystal
    Lim, Wei-Yen
    Soong, Richie
    Wenk, Markus Rene
    Aung, Tin
    Wong, Tien-Yin
    Khor, Chiea-Chuen
    Little, Peter
    Chia, Kee-Seng
    Teo, Yik-Ying
    AMERICAN JOURNAL OF HUMAN GENETICS, 2013, 92 (01) : 52 - 66
12345