共 50 条
- [31] Cryptotanshinione upregulates α-secretase by activation PI3K pathway in cortical neuronsBRAIN RESEARCH, 2010, 1348 : 165 - 173Mei, Zhengrong论文数: 0 引用数: 0 h-index: 0机构: Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R China Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R ChinaSitu, Bing论文数: 0 引用数: 0 h-index: 0机构: Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R China Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R ChinaTan, Xiangping论文数: 0 引用数: 0 h-index: 0机构: Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R China Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R ChinaZheng, Shiming论文数: 0 引用数: 0 h-index: 0机构: Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R China Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R ChinaZhang, Fangyan论文数: 0 引用数: 0 h-index: 0机构: Chongqing Inst Drug Control, Chongqing 401121, Peoples R China Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R ChinaYan, Pengke论文数: 0 引用数: 0 h-index: 0机构: Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R China Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R ChinaLiu, Peiqing论文数: 0 引用数: 0 h-index: 0机构: Sun Yat Sen Univ, Sch Pharmaceut Sci, Lab Pharmacol & Toxicol, Guangzhou 510060, Guangdong, Peoples R China Third Affiliated Hosp, Guangzhou Med Coll, Guangzhou 510150, Guangdong, Peoples R China
- [32] Targeting the PI3K pathway in the brain - pharmacokinetics and efficacy of a PI3k inhibitor optimized to cross the blood-brain barrierDRUG METABOLISM REVIEWS, 2011, 43 : 183 - 183Salphati, Laurent论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAPang, Jodie论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USACheong, Jonathan论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAPlise, Emile G.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAAlicke, Bruno论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USADing, Xiao论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USADotson, Jennafer论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAFeng, Dingzhou论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAHeffron, Tim论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAJoachico, Allan论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USALee, Leslie B.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USANdubaku, Chudi论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USANishimura, Merry论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USANonomiya, Jim论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAOlivero, Alan论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAPhillips, Heidi论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USASideris, Setve论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAWang, Lan论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USAZhang, Xiaolin论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USA
- [33] Targeting the PI3K Pathway in the Brain-Efficacy of a PI3K Inhibitor Optimized to Cross the Blood-Brain BarrierCLINICAL CANCER RESEARCH, 2012, 18 (22) : 6239 - 6248Salphati, Laurent论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAHeffron, Timothy P.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Chem, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAAlicke, Bruno论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Canc Signaling & Translat Oncol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USANishimura, Merry论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Canc Signaling & Translat Oncol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USABarck, Kai论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Biomed Imaging, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USACarano, Richard A.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Biomed Imaging, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USACheong, Jonathan论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAEdgar, Kyle A.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Canc Signaling & Translat Oncol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAGreve, Joan论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Biomed Imaging, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAKharbanda, Samir论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Canc Signaling & Translat Oncol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAKoeppen, Hartmut论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Pathol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USALau, Shari论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Pathol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USALee, Leslie B.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Canc Signaling & Translat Oncol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAPang, Jodie论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAPlise, Emile G.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAPokorny, Jenny L.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Radiat Oncol, Rochester, MN USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAReslan, Hani Bou论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Biomed Imaging, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USASarkaria, Jann N.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Radiat Oncol, Rochester, MN USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAWallin, Jeffrey J.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Canc Signaling & Translat Oncol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAZhang, Xiaolin论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAGould, Stephen E.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Canc Signaling & Translat Oncol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAOlivero, Alan G.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Chem, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USAPhillips, Heidi S.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Canc Signaling & Translat Oncol, San Francisco, CA 94080 USA Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USA
- [34] Targeting the PI3K pathway in cancerEUROPEAN JOURNAL OF CANCER, 2013, 49 : S80 - S80Workman, P.论文数: 0 引用数: 0 h-index: 0机构: UK Ctr Canc Therapeut, Inst Canc Res, Sutton, Surrey, England UK Ctr Canc Therapeut, Inst Canc Res, Sutton, Surrey, England
- [35] Targeting the PI3K pathway in cancerBREAST CANCER RESEARCH AND TREATMENT, 2004, 88 : S4 - S4Mills, GB论文数: 0 引用数: 0 h-index: 0机构: Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA
- [36] The PI3K Pathway in Human DiseaseCELL, 2017, 170 (04) : 605 - 635Fruman, David A.论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USA Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USAChiu, Honyin论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USA Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USAHopkins, Benjamin D.论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Med Coll, Meyer Canc Ctr, 413 E 69th St, New York, NY 10021 USA Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USABagrodia, Shubha论文数: 0 引用数: 0 h-index: 0机构: Pfizer Worldwide Res & Dev, Oncol R&D Grp, 10646-CB4 Sci Ctr Dr, San Diego, CA 92121 USA Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USACantley, Lewis C.论文数: 0 引用数: 0 h-index: 0机构: Weill Cornell Med Coll, Meyer Canc Ctr, 413 E 69th St, New York, NY 10021 USA Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USAAbraham, Robert T.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Worldwide Res & Dev, Oncol R&D Grp, 10646-CB4 Sci Ctr Dr, San Diego, CA 92121 USA Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USA
- [37] Roles of PI3Kγ and PI3Kδ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3Kγ/δ inhibitor duvelisibSCIENTIFIC REPORTS, 2023, 13 (01)Till, Kathleen J.论文数: 0 引用数: 0 h-index: 0机构: Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, England Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, EnglandAbdullah, Mariah论文数: 0 引用数: 0 h-index: 0机构: Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, England Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, EnglandAlnassfan, Tahera论文数: 0 引用数: 0 h-index: 0机构: Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, England Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, EnglandJanet, Gallardo Zapata论文数: 0 引用数: 0 h-index: 0机构: Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, England Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, EnglandMarks, Thomas论文数: 0 引用数: 0 h-index: 0机构: Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, England Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, EnglandComa, Silvia论文数: 0 引用数: 0 h-index: 0机构: Verastem Oncol, 117 Kendrick St 500, Needham, MA USA Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, EnglandWeaver, David T.论文数: 0 引用数: 0 h-index: 0机构: Verastem Oncol, 117 Kendrick St 500, Needham, MA USA Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, EnglandPachter, Jonathan A.论文数: 0 引用数: 0 h-index: 0机构: Verastem Oncol, 117 Kendrick St 500, Needham, MA USA Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, EnglandPettitt, Andrew R.论文数: 0 引用数: 0 h-index: 0机构: Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, England Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, EnglandSlupsky, Joseph R.论文数: 0 引用数: 0 h-index: 0机构: Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, England Univ Liverpool, Inst Syst Mol & Integrat Biol, Dept Mol & Clin Canc Med, Ashton St, Liverpool L69 3GE, England
- [38] PI3K pathway in prostate cancer: All resistant roads lead to PI3KBIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2018, 1870 (02): : 198 - 206Park, Soonbum论文数: 0 引用数: 0 h-index: 0机构: Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South Korea Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South KoreaKim, Young Sik论文数: 0 引用数: 0 h-index: 0机构: Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South Korea Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South KoreaKim, Davis Yeon论文数: 0 引用数: 0 h-index: 0机构: Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South Korea Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South KoreaSo, Insuk论文数: 0 引用数: 0 h-index: 0机构: Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South Korea Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South KoreaJeon, Ju-Hong论文数: 0 引用数: 0 h-index: 0机构: Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South Korea Seoul Natl Univ, Coll Med, Inst Human Environm Interface Biol, Dept Physiol & Biomed Sci, 103 Daehak Ro, Seoul 03080, South Korea
- [39] Roles of PI3Kγ and PI3Kδ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3Kγ/δ inhibitor duvelisibScientific Reports, 13Kathleen J. Till论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative BiologyMariah Abdullah论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative BiologyTahera Alnassfan论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative BiologyGallardo Zapata Janet论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative BiologyThomas Marks论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative BiologySilvia Coma论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative BiologyDavid T. Weaver论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative BiologyJonathan A. Pachter论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative BiologyAndrew R. Pettitt论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative BiologyJoseph R. Slupsky论文数: 0 引用数: 0 h-index: 0机构: University of Liverpool,Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology
- [40] A MAP for PI3K activation on endosomesNature Cell Biology, 2020, 22 : 1292 - 1294Alex G. Batrouni论文数: 0 引用数: 0 h-index: 0机构: Cornell University,Department of Chemistry and Chemical Biology and Weill Institute for Cell and Molecular BiologyJeremy M. Baskin论文数: 0 引用数: 0 h-index: 0机构: Cornell University,Department of Chemistry and Chemical Biology and Weill Institute for Cell and Molecular Biology