Direct Amidation from Alcohols and Amines through a Tandem Oxidation Process Catalyzed by Heterogeneous-Polymer-Incarcerated Gold Nanoparticles under Aerobic Conditions

被引：38

作者：

Soule, Jean-Francois ^{[1
]}

Miyamura, Hiroyuki ^{[1
]}

Kobayashi, Shu ^{[1
]}

机构：

[1] Univ Tokyo, Sch Sci, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2013年 / 8卷 / 11期

基金：

日本学术振兴会; 日本科学技术振兴机构;

关键词：

alcohols; amides; heterogeneous catalysis; nanoparticles; oxidation; DEHYDROGENATIVE AMIDE SYNTHESIS; SUPPORTED GOLD; MOLECULAR-OXYGEN; CARBONYLATION REACTIONS; NANOCLUSTER CATALYSTS; ATMOSPHERIC-PRESSURE; EFFICIENT SYNTHESIS; N-FORMYLATION; THIO ACIDS; ALDEHYDES;

D O I：

10.1002/asia.201300733

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe herein a highly elegant and suitable synthesis of amide products from alcohols and amines through a tandem oxidation process that uses molecular oxygen as a terminal oxidant. Carbon-black-stabilized polymer-incarcerated gold (PICB-Au) or gold/cobalt (PICB-Au/Co) nanoparticles were employed as an efficient heterogeneous catalyst depending on alcohol reactivity and generated only water as the major co-product of the reaction. A wide scope of substrate applicability was shown with 42 examples. The catalysts could be recovered and reused without loss of activity by using a simple operation.

引用

页码：2614 / 2626

页数：13