Distinguishing Truncated and Normal MUC1 Glycoform Targeting from Tn-MUC1-Specific CAR T Cells: Specificity Is the Key to Safety

被引:20
|
作者
Posey, Avery D., Jr. [1 ,2 ]
Clausen, Henrik [3 ,4 ]
June, Carl H. [1 ,2 ]
机构
[1] Univ Penn, Ctr Cellular Immunotherapies, Philadelphia, PA 19104 USA
[2] Univ Penn, Parker Inst Canc Immunotherapy, Philadelphia, PA 19104 USA
[3] Univ Copenhagen, Fac Hlth Sci, Copenhagen Ctr Glyc, Dept Cellular & Mol Med, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark
[4] Univ Copenhagen, Fac Hlth Sci, Copenhagen Ctr Glyc, Dept Odontol, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark
关键词
CHIMERIC ANTIGEN RECEPTOR; PROTEIN;
D O I
10.1016/j.immuni.2016.10.015
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:947 / 948
页数:2
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