An iterative approach to novel polyamines via nucleophilic ring-opening of aziridinium ions with β-amino alcohols

被引:13
|
作者
McKay, C [1 ]
Wilson, RJ [1 ]
Rayner, CM [1 ]
机构
[1] Univ Leeds, Dept Chem, Leeds LS2 9JT, W Yorkshire, England
关键词
D O I
10.1039/b401447b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An iterative procedure for the synthesis of a novel class of synthetic polyamines has been developed, utilising the regioselective ring-opening of aziridinium ion intermediates; facile N-allyl deprotection of intermediate polyamines allows the rapid construction of high molecular weight, stereochemically defined compounds in a convergent manner.
引用
收藏
页码:1080 / 1081
页数:2
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