New nitrogenous germacranes from a Thai marine sponge, Axinyssa n. sp.

被引:12
|
作者
Satitpatipan, V [1 ]
Suwanborirux, K [1 ]
机构
[1] Chulalongkorn Univ, BMNCU, Fac Pharmaceut Sci, Dept Pharmacognosy, Bangkok 10330, Thailand
来源
JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 03期
关键词
D O I
10.1021/np030349a
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Two new germacrane sesquiterpenes, including (1Z,4Z)-7alphaH-11-aminogermacra-1(10),4-diene (1) and N,N'-11-bis[(1Z,4Z)-7alphaH-germacra-1(10),4-dienyl]urea (2), were isolated from a Thai marine sponge Axinyssa n. sp. collected from the Andaman Sea. The structure elucidations of 1 and 2 were accomplished by means of 1D and 2D NMR, MS, and IR spectroscopy. Only 1 exhibited strong antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, and Candida albicans.
引用
收藏
页码:503 / 505
页数:3
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