Encapsulation of CdSe/ZnSe quantum dots by liposome complexes

被引：10
|
作者：
Shan, GY [1 ]
Li, D
Feng, LY
Kong, XG
Liu, YC
Bai, YB
Li, TJ
Sun, JZ
机构：
[1] Jilin Univ, Coll Chem, Changchun 130023, Peoples R China
[2] Chinese Acad Sci, Changchun Inst Opt Fine Mech & Phys, Key Lab Excited State Proc, Changchun 130033, Peoples R China
[3] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2005年 / 23卷 / 12期
关键词：
quantum dot; liposome; immunoassay;
D O I：
10.1002/cjoc.200591688
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A general method was developed to encapsulate CdSe/ZnSe quantum dots by phospholipids liposome complexes, which rendered the quantum dots water-soluble and biocompatible. The encapsulation process was confirmed by transmission electron microscopy and photoluminescence spectroscopy. The photoluminescence of CdSe/ZnSe quantum dots in the liposome complexes was quite stable; their fluorescence remained in the same order of magnitude even after 90 min of photobleaching. CdSe/ZnSe quantum dots in the liposome complexes were further applied as fluorescence marker in immune assay for the detection of rat monoclonal CD95 antibodies. Quantum dots encapsulated by this facile strategy could also be applied in DNA, enzyme and cell labeling, and contribute a lot to the development of in vivo imaging and probing of tissues.
引用
收藏
页码：1688 / 1692
页数：5
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