The Statistical Properties of Protein Folding in the φ4 Theory

被引:0
|
作者
Januar, M. [1 ]
Sulaiman, A. [2 ]
Handoko, L. T. [1 ,3 ]
机构
[1] Univ Indonesia, Dept Phys, Depok 16424, Indonesia
[2] Badan Pengkajian & Penerapan Teknol, Jakarta 10340, Indonesia
[3] Indonesian Inst Sci, Res Ctr Phys, Grp Theoret & Computat Phys, Tangerang 15310, Indonesia
关键词
Protein Folding; Model; Nonlinear; DYNAMICS;
D O I
10.1166/jctn.2013.3175
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The statistical properties of protein folding within the phi(4) model are investigated. The calculation is performed using statistical mechanics and path integral method. In particular, the evolution of heat capacity in term of temperature is given for various levels of the nonlinearity of source and the strength of interaction between protein backbone and nonlinear source. It is found that the nonlinear source contributes constructively to the specific heat especially at higher temperature when it is weakly interacting with the protein backbone. This indicates increasing energy absorption as the intensity of nonlinear sources are getting greater. The simulation of protein folding dynamics within the model is also refined.
引用
收藏
页码:2106 / 2112
页数:7
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