HPV Pathway Profiling: HPV Related Cervical Dysplasia and Carcinoma Studies

被引：0

作者：

Scholl, Susy M. ^{[1
]}

Kamal, Maud ^{[1
]}

De Koning, Leanne ^{[1
]}

Kereszt, Attila ^{[2
]}

Jordanova, Ekaterina S. ^{[3
]}

Ungureanu, Sergiu ^{[4
]}

Berns, Els ^{[5
]}

Sastre, Xavier ^{[1
]}

机构：

[1] Inst Curie, Paris, France

[2] SeqOmics, Szeged, Hungary

[3] Ctr Gyneacol Oncol, Amsterdam, Netherlands

[4] Inst Oncol Moldova, Kishinev, Moldova

[5] Erasmus MC, Rotterdam, Netherlands

来源：

CURRENT PHARMACEUTICAL DESIGN | 2013年 / 19卷 / 08期

关键词：

Cervical cancer; HPV; vaccines; omics; targeted therapy; SQUAMOUS-CELL CARCINOMA; COLONY-STIMULATING FACTOR; PHASE PROTEIN MICROARRAYS; TUMOR-SUPPRESSOR PROTEIN; HUMAN-PAPILLOMAVIRUS DNA; GROWTH-FACTOR RECEPTOR; IGF-BINDING PROTEIN-3; C-MET; FACTOR-I; CONCURRENT CHEMORADIATION;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Cervical cancer is the second most common malignancy among women worldwide. While more than 90% of cervical cancers carry one or more high risk HPV types, the exact relationship between HPV oncoproteins and signaling pathways alterations in cervical cancer remains to be clarified. Vaccines and targeted therapies are today considered of great potential for the improvement of patients' outcome. This review will focus on the interaction of HPV with cervical cancer pathway activations. Next generation high throughput screening technologies for molecular and protein profiling as well as innovative logistics, necessary for the implementation of the personalized care of cervical cancer patients will be discussed.

引用

页码：1379 / 1394

页数：16

共 50 条

[1] Circulating HPV DNA as a biomarker in patients with HPV-related cervical carcinoma
Bryan, S.
Lee, J.
Gunu, R.
Jones, A.
Olaitan, A.
Rosenthal, A.
Bhide, S.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2021, 128 : 60 - 60
[2] Alemtuzumab related HPV infection and cervical dysplasia: real world data
Ruffer, G.
Koniotes, A.
Warren, C.
Bozzali, M.
Fisniku, L.
EUROPEAN JOURNAL OF NEUROLOGY, 2019, 26 : 854 - 854
[3] ALEMTUZUMAB RELATED HPV INFECTION AND CERVICAL DYSPLASIA: REAL WORLD DATA
Ruffer, Giles
Koniotes, Anna
Warren, Catherine
Bozzali, Marco
Fisniku, Leonora
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2019, 90 (12): : E60 - E60
[4] Incidence of HPV and HPV related dysplasia in elderly women in Sweden
Lanner, Lars
Lindstrom, Annika Kristina
PLOS ONE, 2020, 15 (03):
[5] HPV prevalence and HPV-related dysplasia in elderly women
Hermansson, Ruth S.
Olovsson, Matts
Hoxell, Emelie
Lindstrom, Annika K.
PLOS ONE, 2018, 13 (01):
[6] HPV AND CERVICAL-CARCINOMA
COUGOIRE, J
CANCER JOURNAL - FRANCE, 1992, 5 (02): : 72 - 72
[7] HPV73 in cervical cancer and distribution of HPV73 variants in cervical dysplasia
Borgfeldt, Christer
Soderlund-Strand, Anna
Flygh, Lotten Darlin
Forslund, Ola
INTERNATIONAL JOURNAL OF CANCER, 2021, 149 (04) : 936 - 943
[8] Incidence of high risk HPV (HR-HPV) and cervical dysplasia in Nigeria
Umenyl, Chito
Schnatz, Peter
Waszczak, Wendy
Mandavilli, Srinivas R.
CANCER CYTOPATHOLOGY, 2007, 111 (05): : 378 - 378
[9] HPV RELATED CERVICAL CARCINOSARCOMA
Jansa, Vid
Cvjeticanin, Branko
Kovac, Luka
Barbic, Matija
Blaganje, Mija
Staric, Kristina Drusany
Stefanovska, Marina Jakimovska
Macek, Katja Jakopic
Suster, Natasa Kenda
Kunic, Tina
Smrkolj, Spela
Lasic, Mateja
Distefano, Rosario Emanuele Carlo
Pirs, Bostjan
Meglic, Leon
Kobal, Borut
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2023, 33 : A101 - A101
[10] The incidence of HPV and cervical dysplasia in rural Nigeria
Markelova, N
Schnatz, PF
Holmes, D
Harp, J
Stevens, K
Hodges, K
Waszczak, W
Mandavilli, SR
LABORATORY INVESTIGATION, 2005, 85 : 72A - 72A

← 1 2 3 4 5 →