Oocyte and embryo quality: Do the apoptotic markers have a place in the preimplantation genetic diagnostic?

被引：8
|
作者：
Haouzi, D. [1 ,2 ,3 ]
De Vos, J. [1 ,3 ]
Loup, V. [1 ,2 ,3 ]
Assou, S. [1 ,3 ]
Gasca, S. [1 ,2 ,3 ]
Reyftmann, L. [2 ]
Klein, B. [1 ,3 ]
Hamamah, S. [1 ,2 ,3 ]
机构：
[1] CHU Montpellier, Hop St Eloi, Inst Rech Biotherapie, F-34295 Montpellier 5, France
[2] CHU Montpellier, Hop Arnaud Villeneuve, Serv Gynecol Obstet, Dept Med & Biol Reprod, F-34295 Montpellier 5, France
[3] INSERM, U847, Montpellier, France
来源：
GYNECOLOGIE OBSTETRIQUE & FERTILITE | 2008年 / 36卷 / 7-8期
关键词：
Assisted Reproductive Technologies (ART); apoptosis; genetic control; oocyte; embryo; IVF; microenvironment; diagnosis;
D O I：
10.1016/j.gyobfe.2008.02.028
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
In Assisted Reproductive Technology (ART), the pregnancy and birth rates following in vitro fertilization (IVF) attempts are still low. Recently, research in the field of ART has explored new oocyte and embryo quality selection criteria such as apoptotic markers. Many studies provided evidence that bad oocyte and embryo quality can be associated with apoptosis. The aim of this review is to summarize our current knowledge on the apoptosis process in oocytes and embryos, and focus on the possibility of using apoptotic markers as a reliable and predictive marker to select competent oocytes and embryos during IFV. (c) 2008 Elsevier Masson SAS. Tous droits reserves.
引用
收藏
页码：730 / 742
页数：13
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