Fecal calprotectin and fecal indole predict outcome of fecal microbiota transplantation in subjects with recurrent Clostridium difficile infection

被引：12
|
作者：
Hibbard, J. [1 ]
Jiang, Z. -D. [2 ,3 ]
DuPont, H. L. [2 ,3 ,4 ,5 ]
机构：
[1] Ohio Wesleyan Univ, Delaware, OH 43015 USA
[2] Kelsey Res Fdn, Houston, TX USA
[3] Univ Texas Sch Publ Hlth, Houston, TX USA
[4] Univ Texas McGovern Med Sch, 1200 Pressler St,Suite 743, Houston, TX 77030 USA
[5] Baylor Coll Med, Houston, TX 77030 USA
来源：
ANAEROBE | 2019年 / 56卷
关键词：
Calprotectin; Indole; IBD; FMT; C. difficile infection;
D O I：
10.1016/j.anaerobe.2019.03.006
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Fecal calprotectin and indole were studied in 134 subjects with recurrent CDI before and after FMT. Reduced fecal calprotectin (p = 0.0353, 95% CI 0.1305-0.1439) and rising levels of indole (p < 0.0001, 95% CI < 0.0001-0.0003) predicted successful treatment. A ratio of recal calprotectin/indole may provide prognostic value for FMT (p = 0.0004, 95% CI 0.22-0.87). (C) 2019 The Authors. Published by Elsevier Ltd.
引用
收藏
页码：102 / 105
页数：4
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