Expeditious Total Syntheses of Natural Allenic Products via Aromatic Ring Umpolung

被引：59

作者：

Sabot, Cyrille ^{[1
]}

Berard, Didier ^{[1
]}

Canesi, Sylvain ^{[1
]}

机构：

[1] Univ Quebec, Lab Methodol & Synth Produits Nat, Montreal, PQ H3C 3P8, Canada

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 20期

关键词：

D O I：

10.1021/ol801921d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Concise diastereoselective syntheses of the marine (+/-)-panacene and terrestrial (+/-)-desbromopanacene have been achieved in a few steps based on a concept of "aromatic ring umpolung". The synthetic avenue to the (+/-)-panacene involved a novel oxymercuration strategy to produce the correct configuration of the bromoallene moiety.

引用

页码：4629 / 4632

页数：4

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