Antioxidant and androgenic effects of dietary ginger on reproductive function of male diabetic rats

被引:37
|
作者
Ghlissi, Zohra [1 ]
Atheymen, Rim [1 ]
Boujbiha, Mouhamed Ali [2 ]
Sahnoun, Zouheir [1 ]
Ayedi, Fatma Makni [3 ]
Zeghal, Khaled [1 ]
El Feki, Abdelfattah [2 ]
Hakim, Ahmed [1 ]
机构
[1] Univ Sfax, Fac Med, Pharmacol Lab, Sfax 3029, Tunisia
[2] Univ Sfax, Fac Sci, Lab Anim Ecophysiol, Sfax 3029, Tunisia
[3] Univ Sfax, Fac Med, Biochem Lab, Sfax 3029, Tunisia
关键词
Diabetes; hypofertility; oxidative stress; reproductive function; Zingiber officinale; ZINGIBER-OFFICINALE; OXIDATIVE STRESS;
D O I
10.3109/09637486.2013.812618
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
This study evaluated the antioxidant and androgenic properties of ginger roots on the reproductive function of male diabetic rats. Animals were divided into three groups; the control (Control), diabetic (Diab) and diabetic fed with dietary ginger for 30 d (Diab + Z). Thereafter, blood samples were collected and reproductive organs (testis, epididymis, prostate and seminal vesicle) were removed for determination of sperm parameters, malondialdehyde (MDA) level, glutathione peroxidase (GPx), superoxide dismutase (SOD), catalase (CAT), lactate dehydrogenase (LDH), alkaline phosphatase (ALP) and aspartate and lactate aminotransferase (AST and ALT) activities. Dietary ginger decreased blood glucose and MDA level, increased reproductive organ weights and testosterone level, improved semen quantity and motility, and ameliorated the SOD, CAT and GPx activities as well as testis AST, ALT, LDH and ALP activities. Intake of ginger roots improves the antioxidant and androgenic reproductive function of male diabetic rats in addition to its antidiabetic property.
引用
收藏
页码:974 / 978
页数:5
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