Colchicine intoxication and infection risk: a case report

被引：12

作者：

Kocak, Z. ^{[1
]}

Akay, H. ^{[2
]}

Gucenmez, S. ^{[2
]}

Tufan, A. ^{[3
]}

Donderici, O. ^{[2
]}

机构：

[1] Ankara Res & Training Hosp, Infect Dis & Clin Microbiol Dept, TR-06340 Ankara, Turkey

[2] Ankara Res & Training Hosp, Dept Internal Med, TR-06340 Ankara, Turkey

[3] Ulus Govt Hosp, Dept Internal Med, Ankara, Turkey

来源：

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 2008年 / 33卷 / 04期

关键词：

colchicine; infection; intoxication; leukocyte dysfunction;

D O I：

10.1111/j.1365-2710.2008.00927.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Colchicine is widely used, primarily for the treatment of gouty arthritis and familial Mediterranean fever. Colchicine intoxication is a rare but potentially life-threatening event. Herein, we reported a 26-year-old woman who presented to the emergency department after ingesting 27.5 mg of colchicine in a suicide attempt. She exhibited signs typical of colchicine-poisoning and developed infectious complications but with subsequent complete recovery. This paper discusses the role of colchicine poisoning in increasing susceptibility to infections. This aspect is usually under-appreciated in the clinical picture of colchicine overdose.

引用

页码：451 / 452

页数：2

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