Immunohistochemical reactivity of anti-platelet monoclonal antibodies

被引：1
|
作者：
Simon, M
Dusinsky, R
Horovska, L
Bilka, F
Hluchy, S
机构：
[1] SLOVAK ACAD SCI, INST ANIM BIOCHEM & GENET, IVANKA PRI DUNAJ 90028, SLOVAKIA
[2] UNIV AGR, NITRA 94976, SLOVAKIA
来源：
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | 1996年 / 52卷 / 04期
关键词：
cattle; CD; fibrinogen; histochemistry; monoclonal antibodies;
D O I：
10.1016/0165-2427(96)05590-0
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Ten mAbs of preliminary clusters PC13 and PC27 with specificity for bovine platelets were studied by immunohistochemistry. Cryostat sections of bovine lymph node, spleen, thymus, small intestine, liver, kidney and smears of bone marrow cells were used. Five mAbs (CAPP2, IVA30, IVA125, IL-Al64 and IL-A166) assigned to cluster PC13 (CD41/CD61) stained platelets and non-lymphocytic cells of various tissues. Our data confirm the presence of two specificities in PC27: three mAbs (IVA120, IVA197 and IVA198) specific for fibrinogen strongly reacted with the endothelial and reticular tissues whereas the other two mAbs Co-3D1D4 and Bufl3 (WC13) were negative.
引用
收藏
页码：377 / 382
页数：6
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