High genetic diversity of noroviruses in children from a community-based study in Rio de Janeiro, Brazil, 2014-2018

被引：16
|
作者：
Cantelli, Carina Pacheco [1 ,2 ]
Marques da Silva, Marcelle Figueira [3 ]
Fumian, Tulio Machado [2 ]
da Cunha, Denise Cotrim [4 ]
Ribeiro de Andrade, Juliana da Silva [2 ]
Malta, Fabio Correia [2 ]
da Silva e Mouta Junior, Sergio [2 ]
Fialho, Alexandre Madi [2 ]
Baroni de Moraes, Marcia Terezinha [2 ]
Brasil, Patricia [5 ]
Miagostovich, Marize Pereira [2 ]
Gagliardi Leite, Jose Paulo [2 ]
机构：
[1] Fiocruz MS, Technol Inst Immunobiol Biomanguinhos, Ave Brasil 4365, Manguinho, RJ, Brazil
[2] Fiocruz MS, Oswaldo Cruz Inst, Lab Comparat & Environm Virol, Ave Brasil 4365, BR-21040360 Manguinho, RJ, Brazil
[3] Univ Fed Goias, Trop Pathol & Publ Hlth Inst, Rua 235, Goiania, Go, Brazil
[4] Fiocruz MS, Sergio Arouca Publ Hlth Natl Sch, Ave Brasil 4365, Manguinho, RJ, Brazil
[5] Fiocruz MS, Evandro Chagas Natl Inst Infect Dis, Ave Brasil 4365, Manguinho, RJ, Brazil
来源：
ARCHIVES OF VIROLOGY | 2019年 / 164卷 / 05期
关键词：
MOLECULAR CHARACTERIZATION; RECOMBINANT GII.P16-GII.2; UNITED-STATES; GASTROENTERITIS; PREVALENCE; INFECTION; EPIDEMIOLOGY; EMERGENCE;
D O I：
10.1007/s00705-019-04195-z
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We report on the occurrence and diversity of noroviruses in children (younger than 5 years old of age) from a low-income urban area in Rio de Janeiro, Brazil. Sixty-one stool specimens collected from children between 1 and 4 years old with acute diarrhoeic episodes (ADE) and non-ADE were investigated. RT-qPCR and sequencing of PCR products after conventional RT-PCR analysis were performed. Noroviruses were detected in 29 (47.5%) samples: 21 (46.7%) from cases with ADE and 8 (50%) from non-ADE cases. Molecular characterization showed 10 different genotypes circulating in this community between November 2014 and April 2018.
引用
收藏
页码：1427 / 1432
页数：6
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