SNP-DEPENDENT CYP1A1 INDUCTION: GENETIC VARIATION NEAR BUT NOT IN XRES MODULATES ARYL HYDROCARBON RECEPTOR FUNCTION.

被引:0
|
作者
Liu, D. [1 ]
Qin, S. [1 ]
Krishna, K. [1 ]
Wang, L. [1 ]
Weinshilboum, R. [1 ]
机构
[1] Mayo Clin, Rochester, MN USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
PI-068
引用
收藏
页码:S37 / S38
页数:2
相关论文
共 50 条
  • [31] A CRISPR/Cas9 Whole-Genome Screen Identifies Genes Required for Aryl Hydrocarbon Receptor-Dependent Induction of Functional CYP1A1
    Sundberg, Christopher D.
    Hankinson, Oliver
    TOXICOLOGICAL SCIENCES, 2019, 170 (02) : 310 - 319
  • [32] Aryl hydrocarbon receptor protein and Cyp1A1 gene induction by LPS and phenanthrene in Atlantic cod (Gadus morhua) head kidney cells
    Holen, Elisabeth
    Olsvik, Pal Asgeir
    FISH & SHELLFISH IMMUNOLOGY, 2014, 40 (02) : 384 - 391
  • [33] Dexamethasone accelerates degradation of aryl hydrocarbon receptor (AHR) and suppresses CYP1A1 induction in placental JEG-3 cell line
    Stejskalova, Lucie
    Rulcova, Alice
    Vrzal, Radim
    Dvorak, Zdenek
    Pavek, Petr
    TOXICOLOGY LETTERS, 2013, 223 (02) : 183 - 191
  • [34] Induction of Cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: Results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro
    Hu, Wenyue
    Sorrentino, Claudio
    Denison, Michael S.
    Kolaja, Kyle
    Fielden, Mark R.
    MOLECULAR PHARMACOLOGY, 2007, 71 (06) : 1475 - 1486
  • [35] Activated thyroid hormone receptor modulates dioxin-inducible aryl hydrocarbon receptor-mediated CYP1A1 induction in human hepatocytes but not in human hepatocarcinoma HepG2 cells
    Vrzal, Radim
    Vrzalova, Aneta
    Grycova, Aneta
    Dvorak, Zdenek
    TOXICOLOGY LETTERS, 2017, 275 : 77 - 82
  • [36] p-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell Cycle
    Elliott, Althea
    Joiakim, Aby
    Mathieu, Patricia A.
    Duniec-Dmuchowski, Zofia
    Kocarek, Thomas A.
    Reiners, John J., Jr.
    DRUG METABOLISM AND DISPOSITION, 2012, 40 (05) : 1032 - 1040
  • [37] Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially
    Ciolino, HP
    Daschner, PJ
    Yeh, GC
    BIOCHEMICAL JOURNAL, 1999, 340 : 715 - 722
  • [38] Characterization of CYP1B1 and CYP1A1 expression in human mammary epithelial cells: Role of the aryl hydrocarbon receptor in polycyclic aromatic hydrocarbon metabolism
    Larsen, MC
    Angus, WGR
    Brake, PB
    Eltom, SE
    Sukow, KA
    Jefcoate, CR
    CANCER RESEARCH, 1998, 58 (11) : 2366 - 2374
  • [39] Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbon receptor nuclear translocator (Arnt), cytochromes P4501A1 (CYP1A1) and 1B1 (CYP1B1), and inducibility of CYP1A1 and CYP1B1 in human lymphocytes
    Lin, PP
    Hu, SW
    Chang, TH
    TOXICOLOGICAL SCIENCES, 2003, 71 (01) : 20 - 26
  • [40] Involvement of CREM in CYP1A1 induction through ligand-independent activation pathway of aryl hydrocarbon receptor in HepG2 cells
    Sasamori, Eriko
    Shimoyama, Shuji
    Fukushige, Shinichi
    Kikuchi, Hideaki
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2008, 478 (01) : 26 - 35