Theopederins K and L.: Highly potent cytotoxic metabolites from a marine sponge Discodermia species

被引：28
|
作者：
Paul, GK [1 ]
Gunasekera, SP [1 ]
Longley, RE [1 ]
Pomponi, SA [1 ]
机构：
[1] Harbor Branch Oceanog Inst Inc, Div Biomed Marine Res, Ft Pierce, FL 34946 USA
来源：
JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 01期
关键词：
D O I：
10.1021/np0103766
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Theopederins K (1) and L (2) have been isolated from the marine sponge Discodermia sp. collected from Honduras. I and 2 showed in vitro cytotoxicity against P-388 and A-549 cell lines. The isolation, biological activities, and structure elucidation of theopederins K (1) and L (2) are described.
引用
收藏
页码：59 / 61
页数：3
相关论文
共 50 条
  • [41] Peloruside A:: A potent cytotoxic macrolide isolated from the New Zealand marine sponge Mycale sp.
    West, LM
    Northcote, PT
    Battershill, CN
    JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (02): : 445 - 449
  • [42] Clathrins A-C:: Metabolites from a southern Australian marine sponge, Clathria species
    Capon, RJ
    Miller, M
    Rooney, F
    JOURNAL OF NATURAL PRODUCTS, 2000, 63 (06): : 821 - 824
  • [43] POTENT CYTOTOXIC METABOLITES FROM A LEPTOSPHAERIA SPECIES - STRUCTURE DETERMINATION AND CONFORMATIONAL-ANALYSIS
    TAKAHASHI, C
    MINOURA, K
    YAMADA, T
    NUMATA, A
    KUSHIDA, K
    SHINGU, T
    HAGISHITA, S
    NAKAI, H
    SATO, T
    HARADA, H
    TETRAHEDRON, 1995, 51 (12) : 3483 - 3498
  • [44] Bioactive Secondary Metabolites from the Red Sea Marine Verongid Sponge Suberea Species
    Shaala, Lamiaa A.
    Youssef, Diaa T. A.
    Badr, Jihan M.
    Sulaiman, Mansour
    Khedr, Alaa
    MARINE DRUGS, 2015, 13 (04): : 1621 - 1631
  • [45] Haliclonyne, a new highly oxygenated polyacetylene from the marine sponge Haliclona species
    Chill, L
    Miroz, A
    Kashman, Y
    JOURNAL OF NATURAL PRODUCTS, 2000, 63 (04): : 523 - 526
  • [46] Cytotoxic effects of three new metabolites from Red Sea marine sponge, Petrosia sp.
    Abdel-Lateff, Ahmed
    Alarif, Walled M.
    Asfour, Hany Z.
    Ayyad, Seif-Eldin N.
    Khedr, Alaa
    Badria, Farid. A.
    Al-lihaibi, Sultan S.
    ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2014, 37 (03) : 928 - 935
  • [47] Asmarines A-C;: Three novel cytotoxic metabolites from the marine sponge Raspailia sp.
    Yosief, T
    Rudi, A
    Stein, Z
    Goldberg, I
    Gravalos, GMD
    Schleyer, M
    Kashman, Y
    TETRAHEDRON LETTERS, 1998, 39 (20) : 3323 - 3326
  • [48] Asmarines A-C; Three novel cytotoxic metabolites from the marine sponge Raspailia sp.
    Yosief, T.
    Rudi, A.
    Stein, Z.
    Goldberg, I.
    Tetrahedron Letters, 39 (20):
  • [49] Mycapolyols A-F, new cytotoxic metabolites of mixed biogenesis from the marine sponge Mycale izuensis
    Phuwapraisirisan, P
    Matsunaga, S
    Fusetani, N
    ORGANIC LETTERS, 2005, 7 (11) : 2233 - 2236
  • [50] Renieramycin J, a highly cytotoxic tetrahydroisoquinoline alkaloid, from a marine sponge Neopetrosia sp.
    Oku, N
    Matsunaga, S
    van Soest, RWM
    Fusetani, N
    JOURNAL OF NATURAL PRODUCTS, 2003, 66 (08): : 1136 - 1139
12345