Determination of salmon calcitonin by square wave adsorptive stripping voltammetry

被引:6
|
作者
Osteryoung, JG
Wikiel, KJ
机构
[1] Department of Chemistry, North Carolina State University, Raleigh
[2] Technic Inc., Cranston, RI 02910
基金
美国国家科学基金会;
关键词
salmon calcitonin; disulfides; mercury; adsorption; stripping voltammetry; square wave voltammetry;
D O I
10.1016/S0003-2670(97)00356-5
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Salmon calcitonin (SC) was characterized voltammetrically at a mercury electrode by means of cyclic and square wave voltammetry. The voltammetric behavior of SC resembles the voltammetry of other biologically active compounds containing disulfide group(s). The existence of a well shaped peak due to reduction of adsorption SC was exploited to yield a sensitive analytical method for determination of SC concentration. Square wave adsorptive stripping voltammetry allows determination of SC at nanomolar levels. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:65 / 71
页数:7
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