Pitfalls in Diagnosis of Pediatric Clostridium difficile Infection

被引:17
|
作者
Sammons, Julia S. [1 ]
Toltzis, Philip [2 ]
机构
[1] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Div Infect Dis,Dept Infect Prevent & Control, Philadelphia, PA 19104 USA
[2] Case Western Reserve Univ, Sch Med, Rainbow Babies & Childrens Hosp, Div Pediat Crit Care, Cleveland, OH 44106 USA
关键词
Clostridium difficile; Diagnosis; Diarrhea; Pediatrics; POLYMERASE-CHAIN-REACTION; POINT-PREVALENCE SURVEY; ENZYME-IMMUNOASSAY; STOOL SAMPLES; RISK-FACTORS; GLUTAMATE-DEHYDROGENASE; YOUNG-CHILDREN; UNITED-STATES; TOXIN; INFANTS;
D O I
10.1016/j.idc.2015.05.010
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The incidence of Clostridium difficile infection (CDI) has risen among children and C difficile is increasingly recognized as an important cause of healthcare-associated diarrhea among pediatric patients. Still, increased identification of CDI in healthy children in the community and increased testing among infants requires cautious interpretation, given the high prevalence of asymptomatic colonization in young infants and frequent detection of viruses and other co-pathogens in stool specimens in these age groups. The significance of CDI among infants and the implications of positive C difficile testing among healthy children in the community are areas in need of further study.
引用
收藏
页码:465 / +
页数:13
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