Multifunctionalized Sequence-Defined Oligomers from a Single Building Block

被引：183

作者：

Espeel, Pieter ^{[1
]}

Carrette, Lieselot L. G. ^{[2
]}

Bury, Katarzyna ^{[1
]}

Capenberghs, Sven ^{[1
]}

Martins, Jose C. ^{[3
]}

Du Prez, Filip E. ^{[1
]}

Madder, Annemieke ^{[2
]}

机构：

[1] Univ Ghent, Dept Organ Chem, Polymer Chem Res Grp, B-9000 Ghent, Belgium

[2] Univ Ghent, Dept Organ Chem, Organ & Biomimet Chem Res Grp, B-9000 Ghent, Belgium

[3] Univ Ghent, Dept Organ Chem, NMR & Struct Anal Res Grp, B-9000 Ghent, Belgium

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 50期

关键词：

chemoselectivity; sequence-defined oligomers; solid-phase synthesis; synthetic methods; thiolactone; PHASE PEPTIDE-SYNTHESIS; PRECISION POLYMERS; SYNTHETIC-POLYMERS; ONE-POT; POLYMERIZATION; MONOMER; COVALENT; AMINE; CLICK; THIOL;

D O I：

10.1002/anie.201307439

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Another link in the chain: A thiolactone-based approach for the preparation of multifunctionalized sequence-defined oligomeric structures on solid support was established. The iterative aminolysis/chain extension method with a single building block and a variety of commercial amines allowed for the protecting group free synthesis of various oligomeric motifs with a unique backbone and a preprogrammed organization of side chain functionalities. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：13261 / 13264

页数：4

共 50 条

[1] Sequence-Defined Oligomers from Hydroxyproline Building Blocks for Parallel Synthesis Applications
Kanasty, Rosemary L.
Vegas, Arturo J.
Ceo, Luke M.
Maier, Martin
Charisse, Klaus
Nair, Jayaprakash K.
Langer, Robert
Anderson, Daniel G.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 55 (33) : 9529 - 9533
[2] Oxidative degradation of sequence-defined peptoid oligomers
Schunk, Hattie C.
Austin, Mariah J.
Taha, Bradley Z.
McClellan, Matthew S.
Suggs, Laura J.
Rosales, Adrianne M.
MOLECULAR SYSTEMS DESIGN & ENGINEERING, 2023, 8 (01) : 92 - 104
[3] Bioinspired sequence-defined oligomers and their biological applications
Alabi, Christopher
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
[4] Charge Transport in Sequence-Defined Conjugated Oligomers
Yu, Hao
Li, Songsong
Schwieter, Kenneth E.
Liu, Yun
Sun, Boran
Moore, Jeffrey S.
Schroeder, Charles M.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 142 (10) : 4852 - 4861
[5] Isotope Ratio Encoding of Sequence-Defined Oligomers br
Zwillinger, Marton
Fischer, Lucile
Salyi, Gergo
Szabo, Soma
Csekei, Marton
Huc, Ivan
Kotschy, Andras
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 144 (41) : 19078 - 19088
[6] Sequence-defined acrylate oligomers: Synthesis optimization and upscaling
Junkers, Thomas
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
[7] Discrete multifunctional sequence-defined oligomers with controlled chirality
Li, Jie
Leclercq, Maxime
Fossepre, Mathieu
Surin, Mathieu
Glinel, Karine
Jonas, Alain M.
Fernandes, Antony E.
POLYMER CHEMISTRY, 2020, 11 (24) : 4040 - 4046
[8] Sequence-defined oligomers based on a thiolactone strategy: From manual to automated approach
Martens, Steven
Du Prez, Filip
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
[9] Sequence-Defined Conjugated Oligomers in Donor-Acceptor Dyads
Mills, Harrison A.
Rahman, Samihat
Zigelstein, Rachel
Xu, Hao
Varju, Bryton R.
Bender, Timothy P.
Wilson, Mark W. B.
Seferos, Dwight S.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 145 (43) : 23519 - 23526
[10] Scalable Synthesis of Sequence-Defined Oligomers via Photoflow Chemistry
Van De Walle, Matthias
De Bruycker, Kevin
Junkers, Tanja
Blinco, James P.
Barner-Kowollik, Christopher
CHEMPHOTOCHEM, 2019, 3 (05): : 225 - 228

← 1 2 3 4 5 →