Transition metal compound mediated reduction of α-amino acids to 1,2-amino alcohols with NaBH4 in water

被引:0
|
作者
Demir, AS [1 ]
Akhmedov, IM [1 ]
Sesenoglu, Ö [1 ]
机构
[1] Middle E Tech Univ, Fac Arts & Sci, Dept Chem, TR-06531 Ankara, Turkey
来源
TURKISH JOURNAL OF CHEMISTRY | 1999年 / 23卷 / 02期
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH4 in the presence of NiCl2 or MoO3 in water give 1,2-amino alcohols in high yield. When optically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.
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页码:123 / 126
页数:4
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