General and facile synthesis of 1,2-amino alcohols

被引：4
|
作者：
Jung, DY [1 ]
Ko, CH [1 ]
Kim, YH [1 ]
机构：
[1] Korea Adv Inst Sci & Technol, Dept Chem, Sch Mol Sci BK21, Ctr Mol Design & Synth, Taejon 305701, South Korea
来源：
SYNLETT | 2004年 / 07期
关键词：
amino alcohol; alpha-amidoalkyl phenylsulfone; benzyloxymethyl lithium; nucleophilic addition; activated imine;
D O I：
10.1055/s-2004-822926
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Facile preparation of 1,2-amino alcohols has been achieved by the reaction of benzyloxymethyl lithium with imines, which are generated from alpha-amido sulfones and benzyloxymethyl lithium in situ at -78degreesC in THF.
引用
收藏
页码：1315 / 1317
页数：3
相关论文
共 50 条
  • [1] Stereoselective synthesis of enantioenriched acetylenic 1,2-amino alcohols
    Chemla, Fabrice
    Ferreira, Franck
    Gaucher, Xavier
    Palais, Laetitia
    SYNTHESIS-STUTTGART, 2007, (08): : 1235 - 1241
  • [2] PRACTICAL EPC SYNTHESIS OF 1,2-AMINO AND 1,3-AMINO ALCOHOLS
    GMEINER, P
    KARTNER, A
    JUNGE, D
    TETRAHEDRON LETTERS, 1993, 34 (27) : 4325 - 4326
  • [3] New, convenient methods of synthesis and resolution of 1,2-amino alcohols
    Periasamy, M
    Sivakumar, S
    Reddy, MN
    SYNTHESIS-STUTTGART, 2003, (13): : 1965 - 1967
  • [4] Synthesis of new tetrazole-containing 1,2-amino alcohols
    Pantileenko, SV
    Petrov, VV
    Ratner, FI
    Shchetinina, TV
    ZHURNAL ORGANICHESKOI KHIMII, 1999, 35 (03): : 479 - 480
  • [5] SYNTHESIS AND PROPERTIES OF ETHOXYMETHYL-SUBSTITUTED 1,2-AMINO ALCOHOLS
    ALLAKHVERDIEV, MA
    ALIEV, AB
    KURBANOV, KB
    KERIMOV, VM
    OMAROV, SM
    JOURNAL OF APPLIED CHEMISTRY OF THE USSR, 1992, 65 (10): : 1908 - 1911
  • [6] A NEW GENERAL SYNTHESIS OF 2-AMINO ALCOHOLS
    BERLINGUET, L
    CANADIAN JOURNAL OF CHEMISTRY, 1954, 32 (01) : 31 - 39
  • [7] Synthesis of functionalized oxazolidines by multicomponent reactions of 1,2-amino alcohols (microreview)
    Xu, Xianjun
    Wei, Hua
    Feng, Huangdi
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2020, 56 (04) : 464 - 466
  • [8] 1,2-amino alcohols and their heterocyclic derivatives as chiral auxiliaries in asymmetric synthesis
    Ager, DJ
    Prakash, I
    Schaad, DR
    CHEMICAL REVIEWS, 1996, 96 (02) : 835 - 875
  • [9] Synthesis of heavily substituted 1,2-amino alcohols in enantiomerically pure form
    García-Delgado, N
    Reddy, KS
    Solà, L
    Riera, A
    Pericàs, MA
    Verdaguer, X
    JOURNAL OF ORGANIC CHEMISTRY, 2005, 70 (18): : 7426 - 7428
  • [10] Facile three-step synthesis of 1,2-amino alcohols using the Ellman homochiral tert-butylsulfinamide.
    Barrow, JC
    Ngo, PL
    Pellicore, JM
    Selnick, H
    Nantermet, PG
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 220 : U49 - U49
12345