OVEREXPRESSION OF ISOCITRATE DEHYDROGENASE 1/2 (IDH1/2) MUTANT PROTEIN RENDERS GLIOMA CELLS MORE SENSITIVE TO RADIATION

被引：0
|
作者：
Li, Sichen [1 ]
Chou, Arthur P. [1 ]
Chen, Weidong [1 ]
Chen, Ruihuan [2 ]
Deng, Yuzhong [2 ]
Phillips, Heidi S. [2 ]
Faull, Kym F. [1 ]
Cloughesy, Timothy [1 ]
Liau, Linda M. [1 ]
Lai, Albert [1 ]
机构：
[1] Univ Calif Los Angeles, Los Angeles, CA USA
[2] Genentech Inc, San Francisco, CA 94080 USA
来源：
NEURO-ONCOLOGY | 2012年 / 14卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：129 / 129
页数：1
相关论文
共 50 条
  • [41] Develop mutant isocitrate dehydrogenase 1 (IDH1)-expressing gliomas using RCAS/tv-a technology
    Kim, Youngmi
    Lindberg, Nanna
    Bolouri, Hamid
    Delrow, Jeffrey
    Ozawa, Tatsuya
    Holland, Eric
    CANCER RESEARCH, 2014, 74 (19)
  • [42] IDH1 Overexpression Induced Chemotherapy Resistance and IDH1 Mutation Enhanced Chemotherapy Sensitivity in Glioma Cells in Vitro and in Vivo
    Wang, Ju-Bo
    Dong, Dan-Feng
    Wang, Mao-De
    Gao, Ke
    ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 15 (01) : 427 - 432
  • [43] Mutant IDH1 Promotes Glioma Formation In Vivo
    Philip, Beatrice
    Yu, Diana X.
    Silvis, Mark R.
    Shin, Clifford H.
    Robinson, James P.
    Robinson, Gemma L.
    Welker, Adam E.
    Angel, Stephanie N.
    Tripp, Sheryl R.
    Sonnen, Joshua A.
    VanBrocklin, Matthew W.
    Gibbons, Richard J.
    Looper, Ryan E.
    Colman, Howard
    Holmen, Sheri L.
    CELL REPORTS, 2018, 23 (05): : 1553 - 1564
  • [44] The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells
    Xu, Hui
    Cao, Yu
    Ruan, Jianqiao
    Wang, Fei
    He, Yuhong
    Yang, Lina
    Yu, Tian
    Du, Fang
    Zhang, Ningmei
    Cao, Xiangmei
    JOURNAL OF NEURO-ONCOLOGY, 2024, 170 (01) : 161 - 171
  • [45] Targeting the isocitrate dehydrogenase 1 (IDH1) metabolic enzyme in prostate cancer
    Gonthier, Kevin
    Weidmann, Cindy
    Fregeau-Proulx, Lilianne
    Audet-Walsh, Etienne
    CANCER RESEARCH, 2020, 80 (16)
  • [46] MUTANT IDH1 PROMOTES GLIOMA FORMATION IN VIVO
    Yu, Diana
    Boekholder, Ryan
    VanBrocklin, Matthew
    Sonnen, Joshua
    Colman, Howard
    Holmen, Sheri
    NEURO-ONCOLOGY, 2018, 20 : 272 - 272
  • [47] Wild-Type IDH1 and Mutant IDH1 Opposingly Regulate Podoplanin Expression in Glioma
    Sun, Chao
    Xiao, Liming
    Zhao, Yuanlin
    Shi, Jiankuan
    Yuan, Yuan
    Gu, Yu
    Zhang, Feng
    Gao, Xing
    Yang, Ying
    Yang, Risheng
    Qin, Junhui
    Zhang, Jin
    Wang, Chao
    Wang, Yingmei
    Wang, Zhe
    Hu, Peizhen
    Chang, Ting
    Wang, Liang
    Wang, Gang
    Chen, Huangtao
    Li, Zhuyi
    Ye, Jing
    TRANSLATIONAL ONCOLOGY, 2020, 13 (04):
  • [48] ISOCITRATE DEHYDROGENASE 1 (IDH1) MUTATIONS IN GFAP: V12HA-RAS MOUSE GLIOMA MODEL
    Sabha, Nesrin S.
    Agnihotri, Sameer
    Wolf, Amparo
    Deimling, Andreasvon
    Croul, Sidney
    Guha, Abhijit
    NEURO-ONCOLOGY, 2010, 12 : 133 - 133
  • [49] 5-Azacitidine in patients with IDH1/2-mutant recurrent glioma
    Federici, Laetitia
    Capelle, Laurent
    Annereau, Maxime
    Bielle, Franck
    Willekens, Christophe
    Dehais, Caroline
    Laigle-Donadey, Florence
    Hoang-Xuan, Khe
    Delattre, Jean-Yves
    Idbaih, Ahmed
    Lemare, Francois
    de Botton, Stephane
    Sanson, Marc
    Touat, Mehdi
    NEURO-ONCOLOGY, 2020, 22 (08) : 1226 - 1228
  • [50] From genomics to the clinic: biological and translational insights of mutant IDH1/2 in glioma
    Dunn, Gavin P.
    Andronesi, Ovidiu C.
    Cahill, Daniel P.
    NEUROSURGICAL FOCUS, 2013, 34 (02)
12345