Influenza vaccine in Hajj pilgrims: Policy issues from field studies

被引:27
|
作者
Rashid, Harunor [1 ]
Shafi, Shuja [2 ]
Haworth, Elizabeth
Memish, Ziad A. [3 ]
El Bashira, Haitham [1 ]
Ali, Kamal A. [1 ]
Booy, Robert [1 ,4 ,5 ]
机构
[1] Barts & London Queen Marys Sch Med & Dent, Acad Unit Child Hlth, London E1 2AT, England
[2] Hlth Protect Agcy, London, England
[3] Natl Guard Hlth Affairs, King Abdulaziz Med City, Riyadh, Saudi Arabia
[4] Univ Sydney, Sydney, NSW 2006, Australia
[5] Childrens Hosp, Natl Ctr Immunisat Res & Surveillance Vaccine Pre, Westmead, NSW, Australia
关键词
influenza vaccine; travel; mass gatherings;
D O I
10.1016/j.vaccine.2008.07.001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In pilgrims returning to the UK from the Hajj in 2005 and 2006, protection from PCR-confirmed influenza by influenza vaccine was estimated using verified vaccination histories from those with symptoms consistent with influenza. Of 538 patients whose nasal swabs were analysed and immunisation histories confirmed 115 (21%) were in a high-risk group for influenza; half of these (58/115) were immunised against influenza, compared with a fifth (90/423) of those not at high risk. Five percent of vaccinated 'at risk' pilgrims compared with 14% of unvaccinated (RR 0.37, 95% CI 0.1-1.4) had confirmed influenza. Rates of influenza in vaccinated and unvaccinated 'not at risk' pilgrims were similar (10% vs. 11%). Seasonal influenza vaccine was insignificantly protective against influenza in Hajj pilgrims. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4809 / 4812
页数:4
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