Efficacy of Opicapone at Different Levodopa Regimens up to a Threshold of 600mg/Day Levodopa in Parkinson's Disease Patients with Motor Fluctuations

被引:0
|
作者
LeWitt, Peter A. [1 ,2 ]
Stocchi, Fabrizio [3 ]
Ferreira, Joaquim J. [4 ]
Klepitskaya, Olga [5 ]
Magalhaes, Diogo [6 ,7 ]
Rocha, Jose-Francisco [6 ]
Soares-da-Silva, Patricio [6 ,7 ]
机构
[1] Henry Ford Hosp, West Bloomfield, MI USA
[2] Wayne State Univ, Sch Med, Dept Neurol, West Bloomfield, MI USA
[3] IRCCS San Raffaele Pisana, Dept Neurol, Rome, Italy
[4] Univ Lisbon, Fac Med, Lab Clin Pharmacol & Therapeut, Lisbon, Portugal
[5] Neurocrine Biosci Inc, San Diego, CA USA
[6] BIAL Portela & Ca SA, Coronado, Portugal
[7] Univ Porto, Porto, Portugal
关键词
ADJUNCT;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
490
引用
收藏
页码:S187 / S188
页数:2
相关论文
共 50 条
  • [31] Pharmacokinetics of Opicapone and Effect on COMT and Levodopa Pharmacokinetics in Patients with Parkinson's Disease
    Loewen, G.
    LeWitt, P.
    Olanow, C.
    Kieburtz, K.
    Liang, G.
    Jimenez, R.
    Olson, K.
    Roberts, E.
    [J]. MOVEMENT DISORDERS, 2019, 34 : S62 - S62
  • [32] Ropinirole in the treatment of levodopa-induced motor fluctuations in patients with Parkinson's disease
    Rascol, O
    Lees, AJ
    Senard, JM
    Pirtosek, Z
    Montastruc, JL
    Fuell, D
    [J]. CLINICAL NEUROPHARMACOLOGY, 1996, 19 (03) : 234 - 245
  • [33] Assessment of safety and efficacy of Opicapone add-on to levodopa in Parkinson's disease.
    Ruiz-Lopez, Marta
    Diaz, Lola
    Feliz, Cici
    Garcia-Ruiz, Pedro
    [J]. NEUROLOGY, 2020, 94 (15)
  • [34] Pharmacological Insights into Levodopa-induced Motor Fluctuations in Patients with Parkinson's Disease
    Rascol, Olivier
    [J]. MOVEMENT DISORDERS CLINICAL PRACTICE, 2016, 3 (06): : 523 - 526
  • [35] Amantadine given as adjuvant to levodopa in the treatment of levodopa induced dyskinesias and motor fluctuations in Parkinson's disease
    Oztekin, N.
    Oztekin, F.
    Okkan, H.
    Bilen, S.
    Ak, F.
    [J]. MOVEMENT DISORDERS, 2009, 24 : S272 - S272
  • [36] Entacapone improves motor fluctuations in levodopa-treated Parkinson's disease patients
    Kieburtz, K
    Shoulson, I
    Fahn, S
    McDermott, M
    Koller, W
    LeWitt, P
    Nutt, J
    Kurth, M
    Brewer, M
    Lew, M
    Welsh, M
    Waters, C
    Bennett, J
    RostRuffner, E
    Feigin, A
    Gardiner, I
    Kurlan, R
    Hammerstad, J
    Stone, C
    Jankovic, J
    Beach, J
    Tetrud, J
    Kelker, K
    Standaert, DG
    Growdon, JH
    Tennis, M
    Graefe, K
    Mark, MH
    Kelly, SJ
    Pahwa, R
    McGuire, D
    Hubble, J
    Factor, SA
    Brown, DL
    Tuite, P
    Sime, E
    Lang, DL
    Greene, P
    Winfield, H
    Paulson, G
    Zoog, K
    Weeks, C
    Shults, C
    Fontaine, D
    Juncos, JL
    Wood, C
    Shannon, K
    Jaglin, JA
    Tornabene, J
    Lannon, MC
    [J]. ANNALS OF NEUROLOGY, 1997, 42 (05) : 747 - 755
  • [37] Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial
    Ferreira, Joaquim J.
    Lees, Andrew
    Rocha, Jose-Francisco
    Poewe, Werner
    Rascol, Olivier
    Soares-da-Silva, Patricio
    [J]. LANCET NEUROLOGY, 2016, 15 (02): : 154 - 165
  • [38] Preladenant in patients with Parkinson's disease and levodopa-related motor fluctuations: Short-term efficacy and safety
    Troyer, M. D.
    Grachev, I. D.
    Tendolkar, A.
    DeVries, D. E.
    Timmerman, W.
    Schuiling, M.
    Peeters, P.
    Ho, T.
    Cutler, D.
    [J]. MOVEMENT DISORDERS, 2011, 26 : S144 - S144
  • [39] Evaluating Opicapone as Add-on Treatment to Levodopa/DDCI in Patients with Parkinson's Disease
    Jost, Wolfgang
    [J]. NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2022, 18 : 1603 - 1618
  • [40] Current management of motor fluctuations in patients with advanced Parkinson's disease treated chronically with levodopa
    Melamed, E
    Zoldan, J
    Galili-Mosberg, R
    Ziv, I
    Djaldetti, R
    [J]. JOURNAL OF NEURAL TRANSMISSION-SUPPLEMENT, 1999, (56): : 173 - 183