Synthesis, Structure and Biological Activities of 2,2-Dichloro-1-(4-ethoxyphenyl)-cyclopropanyl Substituted Piperidin-1-yl Ketone

被引：6

作者：

Sun, Na-Bo ^{[1
]}

Jin, Jian-Zhong ^{[1
]}

Lei, Chao ^{[1
]}

Ke, Wei ^{[1
]}

机构：

[1] Zhejiang Shuren Univ, Coll Biol & Environm Engn, Hangzhou 310015, Zhejiang, Peoples R China

来源：

ASIAN JOURNAL OF CHEMISTRY | 2013年 / 25卷 / 07期

关键词：

Pyrethroid; Cycloprothrin; Piperidine; Synthesis; Structure; CRYSTAL-STRUCTURE; CYCLOPROPANE MOIETY; DFT CALCULATION; ANTIFUNGAL ACTIVITY; DERIVATIVES; BIOACTIVITY;

D O I：

10.14233/ajchem.2013.14040

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ten new amide-type compounds, which are pyrethroids containing piperidine, are synthesized from 1-(4-ethyoxyphenyl)-2,2-dichlorocyclopropane-1-carboxylic acid and substituted piperidine. Their structures were confirmed by H-1 NMR, MS and elemental analysis. The crystal structure of 4a and 4h were determined by X-ray diffraction analysis. The bioassay results indicated that they showed moderate activity.

引用

页码：4067 / 4070

页数：4

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