Pyrrole-based partial peptidic mimic of neurotensin (8-13): Design and synthesis

被引：2
|
作者：
Zaidi, JH [1 ]
Naeem, F
Ambreen, N
Khan, KM
Pang, YP
Cusack, B
Richelson, E
Anwar, A
Voelter, W
机构：
[1] Quaid I Azam Univ, Dept Chem, Islamabad, Pakistan
[2] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan
[3] Mayo Fdn Med Educ & Res, Neurochem & Neuropharmacol Res, Jacksonville, FL 32224 USA
[4] Univ Tubingen, Interfak Inst Biochem, D-72076 Tubingen, Germany
来源：
LETTERS IN ORGANIC CHEMISTRY | 2006年 / 3卷 / 01期
关键词：
neurotensin; partial peptidic mimic; drug design; synthesis;
D O I：
10.2174/157017806774964530
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.
引用
收藏
页码：21 / 24
页数：4
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