Design and synthesis of intrinsically cell-penetrating nucleopeptides

被引：21
|
作者：
Geotti-Bianchini, Piero [1 ,2 ]
Beyrath, Julien [2 ]
Chaloin, Olivier [2 ]
Formaggio, Fernando [1 ]
Bianco, Alberto [2 ]
机构：
[1] Univ Padua, Dipartimento Chim, I-35131 Padua, Italy
[2] CNRS, Inst Biol Mol & Cellulaire, Lab Immunol & Chim Therapeut, F-67000 Strasbourg, France
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2008年 / 6卷 / 20期
关键词：
D O I：
10.1039/b811639c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Nucleopeptides, which are constituted of a-amino acids bearing nucleobases at their side chains, are able to penetrate into cells and to reach the nucleus without cytotoxic effects.
引用
收藏
页码：3661 / 3663
页数：3
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