Cross-trial analysis of immunological and clinical data resulting from phase I and II trials of MVA-5T4 (TroVax®) in colorectal, renal and prostate cancer patients

被引：0
|
作者：
Harrop, R. [1 ]
Shingler, W. H. [1 ]
Drury, N. [1 ]
Goonewardena, M. [1 ]
de Belin, J. [1 ]
Naylor, S. [1 ]
Treasure, P. [1 ]
机构：
[1] Peter Treasure Stat Serv Ltd, NA, Cambridge, England
来源：
EJC SUPPLEMENTS | 2008年 / 6卷 / 12期
关键词：
D O I：
10.1016/S1359-6349(08)72535-7
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：188 / 188
页数：1
相关论文
共 50 条
  • [21] Vaccination of Renal Cell Cancer Patients with Modified Vaccinia Ankara Delivering Tumor Antigen 5T4 (TroVax) Administered with Interleukin 2: A Phase II Trial
    Amato, Robert J.
    Shingler, William
    Naylor, Stuart
    Jac, Jaroslaw
    Willis, James
    Saxena, Somyata
    Hernandez-McClain, Joan
    Harrop, Richard
    CLINICAL CANCER RESEARCH, 2008, 14 (22) : 7504 - 7510
  • [22] Clinical prognostic factors associated with outcome in renal cell cancer (RCC) patients treated with modified vaccinia ankara plus tumor-associated antigen 5T4 (MVA-5T4)
    Pandey, Prasamsa
    Xiong, Youxin
    Zhang, Yufeng
    Stepankiw, Mika
    Amato, Robert J.
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [23] Extended Immunological Analysis of Two Phase I Clinical Trials of MVA-BN®-HER2 in HER-2 Overexpressing Metastatic Breast Cancer Patients
    Legrand, Fatema A.
    Owen, Rachel
    Delacher, Michael
    Nguyen, Anh-Tuan
    Reimer, Ulf
    Wensucht, Holger
    Laus, Reiner
    Godfrey, Wayne
    Delcayre, Alain
    JOURNAL OF IMMUNOTHERAPY, 2010, 33 (08) : 900 - 900
  • [24] A phase II trial to assess the activity of MVA 5T4 plus interleukin-2 in patients (PTS) with metastatic renal cell carcinoma (MRCC)
    Amato, Robert J.
    Gary, Amanda
    Mostorino, Rosa
    Mayla, Rahul
    Khan, Muhammad
    McDonald, Michael
    Naylor, Stuart
    Harrop, Richard
    ANNALS OF ONCOLOGY, 2006, 17 : 154 - 154
  • [25] Vaccination of prostate cancer patients with modified vaccinia ankara delivering the tumor antigen 5T4: A phase II trial
    Amato, R.
    Drury, N.
    Naylor, S.
    Jac, J.
    Saxena, S.
    Hernandez-McClain, J.
    Harrop, R.
    ANNALS OF ONCOLOGY, 2008, 19 : 37 - 37
  • [26] A vaccinia-based vaccine (TroVax) targeting the oncofetal antigen 5T4 administered before and after surgical resection of colorectal cancer liver metastases: Phase II trial.
    Dangoor, A.
    Burt, D.
    Harrop, R.
    Drury, N.
    Hamer, C.
    Andrews, D.
    Sherlock, D.
    Stern, P.
    Hawkins, R.
    JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (18) : 118S - 118S
  • [27] Raltitrexed (Tomudex™) in combination with 5-fluorouracil for the treatment of patients with advanced colorectal cancer:: Preliminary results from phase I clinical trials
    Schwartz, GK
    Harstrick, A
    Barón, MG
    EUROPEAN JOURNAL OF CANCER, 1999, 35 : S9 - S13
  • [28] Safety and immunogenicity of novel 5T4 viral vectored vaccination regimens in early stage prostate cancer: a phase I clinical trial
    Cappuccini, Federica
    Bryant, Richard
    Pollock, Emily
    Carter, Lucy
    Verrill, Clare
    Hollidge, Julianne
    Poulton, Ian
    Baker, Megan
    Mitton, Celia
    Baines, Andrea
    Meier, Armin
    Schmidt, Guenter
    Harrop, Richard
    Protheroe, Andrew
    MacPherson, Ruth
    Kennish, Steven
    Morgan, Susan
    Vigano, Selena
    Romero, Pedro J.
    Evans, Thomas
    Catto, James
    Hamdy, Freddie
    Hill, Adrian V. S.
    Redchenko, Irina
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 (01)
  • [29] Vaccination of renal cell cancer (RCC) patients with modified vaccinia ankara delivering the tumor antigen 5T4 (TroVax [T]) administered plus low dose interleukin-2 (IL-2): A phase II trial
    Hernandez-McClain, J.
    Amato, R. J.
    Shingler, W. H.
    Naylor, S.
    Jac, J.
    Willis, J. P.
    Saxena, S.
    Harrop, R.
    JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15)
  • [30] Vaccination of Renal Cell Cancer Patients With Modified Vaccinia Ankara Delivering the Tumor Antigen 5T4 (TroVax) Alone or Administered in Combination With Interferon-α (IFN-α) A Phase 2 Trial
    Amato, Robert J.
    Shingler, William
    Goonewardena, Madusha
    de Belin, Jackie
    Naylor, Stuart
    Jac, Jaroslaw
    Willis, James
    Saxena, Somyata
    Hernandez-McClain, Joan
    Harrop, Richard
    JOURNAL OF IMMUNOTHERAPY, 2009, 32 (07) : 765 - 772
12345